ID   Y915_MYCBO              Reviewed;         285 AA.
AC   P59970; A0A1R3XXP9; X2BGE9;
DT   31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Uncharacterized protein Mb0915c;
GN   OrderedLocusNames=BQ2027_MB0915C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SIMILARITY: Belongs to the adenylyl cyclase class-4/guanylyl cyclase
CC       family. {ECO:0000255|PROSITE-ProRule:PRU00099}.
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DR   EMBL; LT708304; SIT99513.1; -; Genomic_DNA.
DR   RefSeq; NP_854572.1; NC_002945.3.
DR   RefSeq; WP_003404644.1; NC_002945.4.
DR   AlphaFoldDB; P59970; -.
DR   SMR; P59970; -.
DR   EnsemblBacteria; SIT99513; SIT99513; BQ2027_MB0915C.
DR   PATRIC; fig|233413.5.peg.996; -.
DR   OMA; HVGSARS; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; -; 2.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; SSF55073; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..285
FT                   /note="Uncharacterized protein Mb0915c"
FT                   /id="PRO_0000074129"
FT   DOMAIN          92..199
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00099"
SQ   SEQUENCE   285 AA;  31190 MW;  681FA6E535D2A9B7 CRC64;
     MLFNAVHNSL PPNIDIDHAI LRGEDHPPTC AKCVARGRIS ALGSLDLRYH SLRCYAAPPD
     VGRCEFVPPR RRVLIANQGL DVSRLPPTGT VTLLLADVEE STHLWQMCPE DMATAIAHLD
     HTVSEAITNH GGVQPVKRYE GDSFVAAFTR ASDAAACALD LQRTSLAPIR LRIGLHTGEV
     QLRDELYVGP TINRTARLRD LAHGGQVVLS AATGDLVTGR LPADAWLVDL GRHPLRGLPR
     PEWVMQLCHP DIREKFPPLR TAKSSPTSIL PAQFTTFVGR RAQIS