ID   Y916_METST              Reviewed;         383 AA.
AC   Q2NFU9;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=UPF0425 pyridoxal phosphate-dependent protein Msp_0916;
GN   OrderedLocusNames=Msp_0916;
OS   Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 /
OS   MCB-3).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX   NCBI_TaxID=339860;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3;
RX   PubMed=16385054; DOI=10.1128/jb.188.2.642-658.2006;
RA   Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R.,
RA   Gottschalk G., Thauer R.K.;
RT   "The genome sequence of Methanosphaera stadtmanae reveals why this human
RT   intestinal archaeon is restricted to methanol and H2 for methane formation
RT   and ATP synthesis.";
RL   J. Bacteriol. 188:642-658(2006).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the UPF0425 family. {ECO:0000305}.
CC   -!- CAUTION: Despite a certain similarity to selA, this is not selA (see AC
CC       Q57622). {ECO:0000305}.
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DR   EMBL; CP000102; ABC57304.1; -; Genomic_DNA.
DR   RefSeq; WP_011406503.1; NC_007681.1.
DR   AlphaFoldDB; Q2NFU9; -.
DR   SMR; Q2NFU9; -.
DR   STRING; 339860.Msp_0916; -.
DR   EnsemblBacteria; ABC57304; ABC57304; Msp_0916.
DR   GeneID; 41325491; -.
DR   KEGG; mst:Msp_0916; -.
DR   eggNOG; arCOG00114; Archaea.
DR   HOGENOM; CLU_055443_0_0_2; -.
DR   OMA; RIDFCSK; -.
DR   OrthoDB; 37272at2157; -.
DR   Proteomes; UP000001931; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR   Gene3D; 3.40.640.10; -; 1.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR020033; PyrdxlP-dep_transferase_arc.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   TIGRFAMs; TIGR03576; pyridox_MJ0158; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate; Reference proteome.
FT   CHAIN           1..383
FT                   /note="UPF0425 pyridoxal phosphate-dependent protein
FT                   Msp_0916"
FT                   /id="PRO_0000285292"
FT   MOD_RES         207
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   383 AA;  42239 MW;  D84D2E9E4485C1AB CRC64;
     MSITLNEVKR REKGLKIIKD KIETDGIDSL IDLTGLAGGF DITPEDISLL ETYAGPAVYE
     QKVQKLGIKH LGGEKILPVN RTTSGIVAMI IALVKPGTKI VHFLAKKPAH PSIPRTAKLV
     GADYEEYTNL DEFKIDDNTS LVFITGTTMD LEVISVEDFK RVIKQAKEKD VIVAVDDASG
     ARIRRAVYNQ PTAIDLGADI SVTSTDKLME GPRGGLMAGS TEIIDKIKLV VNQYGLEAQA
     PLIVGMIKGL EKYSPERIQE AFKQKDELYQ KLLDKQLNPQ TTPTGFMFKE EEIKAEVEKR
     GAKVDMDADV IATVYSMLLI DNYNIITIPA VGMPGASKTV RFDWAAKDSD KLTMDELVSA
     VCDTFDKTVE VCKNNDFESV LYN