ID   Y932_METKA              Reviewed;         523 AA.
AC   Q8TWU9;
DT   31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Uncharacterized protein MK0932;
GN   OrderedLocusNames=MK0932;
OS   Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938).
OC   Archaea; Euryarchaeota; Methanopyri; Methanopyrales; Methanopyraceae;
OC   Methanopyrus.
OX   NCBI_TaxID=190192;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938;
RX   PubMed=11930014; DOI=10.1073/pnas.032671499;
RA   Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA   Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A.,
RA   Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G.,
RA   Koonin E.V., Kozyavkin S.A.;
RT   "The complete genome of hyperthermophile Methanopyrus kandleri AV19 and
RT   monophyly of archaeal methanogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU01266};
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DR   EMBL; AE009439; AAM02145.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8TWU9; -.
DR   SMR; Q8TWU9; -.
DR   STRING; 190192.MK0932; -.
DR   EnsemblBacteria; AAM02145; AAM02145; MK0932.
DR   KEGG; mka:MK0932; -.
DR   PATRIC; fig|190192.8.peg.975; -.
DR   HOGENOM; CLU_508670_0_0_2; -.
DR   OMA; GLRPYVY; -.
DR   Proteomes; UP000001826; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.30.20; -; 1.
DR   InterPro; IPR006638; Elp3/MiaB/NifB.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR023404; rSAM_horseshoe.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SMART; SM00729; Elp3; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   4: Predicted;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome;
KW   S-adenosyl-L-methionine.
FT   CHAIN           1..523
FT                   /note="Uncharacterized protein MK0932"
FT                   /id="PRO_0000107442"
FT   DOMAIN          193..447
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         212
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         220
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         223
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
SQ   SEQUENCE   523 AA;  57616 MW;  5C3A2766CAF22612 CRC64;
     MSQSVLIVDA LGAGKGWRTR SRDVIGAGPR TVASLLESDY EVSLITYEDL QKLGLDSVMD
     YDTVGVSIMT GDERAARRMF DHTRSRTFRF IGGPGAADPN ALLKTGADAA VIGEAEETLP
     ELLEERGPVR GVYFRRGTEV DFPGPRPISR RFTRVNPEYI RAYAHRWAAR VYVEIVRGCS
     NSCRTTFELP DGRKCSGCGN CREGEGGERW ECPEGIPPGC GFCSVPSIFG PTRSRPLNEV
     VREVRGLVRE GIRRVVLSAS DVLDYGRGDL LTDPRTPPPN VEALRRLLRR TSKHVDVLFV
     ENVKACLLNR EIAELLGEYC RGTSVSVGVE TGDPRLLRAI GKPSTLKEAL RAIRLLRRAG
     LRPHAYFVYG LPGQTMKSAK LTAKAMKRAV EMGAEKITVY RFRPIPASAF GDFPPGPSPR
     NDEASRLIAD TARRLNEALK RRMIGKRIRV YVAEPDLRRP RDAIGWPVKG GPKVRLKGAR
     ELVGTECEVE ITGVVSDKVV SGKVVRILEE IDVEALEGRG VPG