ID   Y934_PORGI              Reviewed;         634 AA.
AC   Q7MVU9;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=UPF0313 protein PG_0934 {ECO:0000255|HAMAP-Rule:MF_01251};
GN   OrderedLocusNames=PG_0934;
OS   Porphyromonas gingivalis (strain ATCC BAA-308 / W83).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC   Porphyromonas.
OX   NCBI_TaxID=242619;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-308 / W83;
RX   PubMed=12949112; DOI=10.1128/jb.185.18.5591-5601.2003;
RA   Nelson K.E., Fleischmann R.D., DeBoy R.T., Paulsen I.T., Fouts D.E.,
RA   Eisen J.A., Daugherty S.C., Dodson R.J., Durkin A.S., Gwinn M.L.,
RA   Haft D.H., Kolonay J.F., Nelson W.C., Mason T.M., Tallon L., Gray J.,
RA   Granger D., Tettelin H., Dong H., Galvin J.L., Duncan M.J., Dewhirst F.E.,
RA   Fraser C.M.;
RT   "Complete genome sequence of the oral pathogenic bacterium Porphyromonas
RT   gingivalis strain W83.";
RL   J. Bacteriol. 185:5591-5601(2003).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01251};
CC       Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3
CC       cysteines and an exchangeable S-adenosyl-L-methionine.
CC       {ECO:0000255|HAMAP-Rule:MF_01251};
CC   -!- SIMILARITY: Belongs to the UPF0313 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01251}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE015924; AAQ66068.1; -; Genomic_DNA.
DR   RefSeq; WP_010956162.1; NC_002950.2.
DR   AlphaFoldDB; Q7MVU9; -.
DR   STRING; 242619.PG_0934; -.
DR   EnsemblBacteria; AAQ66068; AAQ66068; PG_0934.
DR   KEGG; pgi:PG_0934; -.
DR   PATRIC; fig|242619.8.peg.861; -.
DR   eggNOG; COG1032; Bacteria.
DR   HOGENOM; CLU_018288_2_0_10; -.
DR   OMA; TCMYYTG; -.
DR   OrthoDB; 229299at2; -.
DR   BioCyc; PGIN242619:G1G02-868-MON; -.
DR   Proteomes; UP000000588; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.80.30.20; -; 1.
DR   HAMAP; MF_01251; UPF0313; 1.
DR   InterPro; IPR006638; Elp3/MiaB/NifB.
DR   InterPro; IPR020612; Methylthiotransferase_CS.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR023404; rSAM_horseshoe.
DR   InterPro; IPR022946; UPF0313.
DR   InterPro; IPR024560; UPF0313_C.
DR   InterPro; IPR013704; UPF0313_N.
DR   PANTHER; PTHR32331; PTHR32331; 1.
DR   Pfam; PF11842; DUF3362; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   Pfam; PF08497; Radical_SAM_N; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SFLD; SFLDG01069; UPF0313; 1.
DR   SMART; SM00729; Elp3; 1.
DR   TIGRFAMs; TIGR03904; SAM_YgiQ; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome;
KW   S-adenosyl-L-methionine.
FT   CHAIN           1..634
FT                   /note="UPF0313 protein PG_0934"
FT                   /id="PRO_0000076388"
FT   DOMAIN          302..582
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   REGION          607..634
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         316
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT   BINDING         320
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT   BINDING         323
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
SQ   SEQUENCE   634 AA;  73044 MW;  1C223AABB9ADABDD CRC64;
     MAKHHPLTDW LPTSKKEMEA KGWDEADVIL FSGDAYVDHP SFGAAVVGRI LEAEGLRVAI
     VPQPNWRDDL RDFRKLGRPR LFFGVSAGAM DSMVNKYTAN RRLRSEDAYT PDRRSDMRPD
     YPTIVYTRIL KELFPDVPVI VGGIEASLRR LTHYDYWQDK LLPGILYQSG ADLLIYGMGE
     LPLHEIAQRL IAGEPFDSLK SIRQIAYLVP KGKTPVPCEN DRHLFSHEEC LSDKRKQAQN
     FREIEIQSNR YEADRILQAV GDSTIVVNPP FPPMSTAQID QSFDLPYTRL PHPRYKGKII
     SAYEMIKHSV NVHRGCFGGC AFCTISAHQG KFIASRSEAS VLREVKEITE MEDFKGYLSD
     VGGPSANMYK MQGYDLSICK RCKKPSCIHP NVCPNLNADH RPLLDLLRRI DKNPKIKKSF
     IGSGVRMDLL LHNYKDKVLK KAADEYTEDL IVKHVSGRLK VAPEHSSDRV LNLMRKPPFR
     QFAEFTKRFQ RINEAHGLRQ QLIPYFISSH PGCTEEDMAE LAILTKKLDF KLEQIQDFTP
     TPMTLATEMY YTGYHPYTLQ PVYTAIKKEE KMRQHMFFFW YKREEADKIR RELHRIGRPD
     LIAKLFDRTT SSRNDRHTPP STQPRKSKSK SRHS