ID   Y942_METJA              Reviewed;         651 AA.
AC   Q58352;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Probable ATP-dependent helicase MJ0942;
DE            EC=3.6.4.12;
GN   OrderedLocusNames=MJ0942;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC   -!- SIMILARITY: Belongs to the helicase family. DinG subfamily.
CC       {ECO:0000305}.
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DR   EMBL; L77117; AAB98945.1; -; Genomic_DNA.
DR   PIR; F64417; F64417.
DR   RefSeq; WP_010870456.1; NC_000909.1.
DR   AlphaFoldDB; Q58352; -.
DR   SMR; Q58352; -.
DR   STRING; 243232.MJ_0942; -.
DR   PRIDE; Q58352; -.
DR   EnsemblBacteria; AAB98945; AAB98945; MJ_0942.
DR   GeneID; 1451838; -.
DR   KEGG; mja:MJ_0942; -.
DR   eggNOG; arCOG00770; Archaea.
DR   HOGENOM; CLU_012117_2_0_2; -.
DR   InParanoid; Q58352; -.
DR   OMA; QVNPVNE; -.
DR   OrthoDB; 31834at2157; -.
DR   PhylomeDB; Q58352; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IBA:GO_Central.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR006555; ATP-dep_Helicase_C.
DR   InterPro; IPR045028; DinG/Rad3-like.
DR   InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11472; PTHR11472; 1.
DR   Pfam; PF13307; Helicase_C_2; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00491; HELICc2; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA-binding; Helicase; Hydrolase; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..651
FT                   /note="Probable ATP-dependent helicase MJ0942"
FT                   /id="PRO_0000102009"
FT   DOMAIN          6..255
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   DOMAIN          449..638
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT   MOTIF           195..198
FT                   /note="DEAH box"
FT   BINDING         41..48
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
SQ   SEQUENCE   651 AA;  75957 MW;  1E55B13938D315B2 CRC64;
     MEFKGYIKEK FPYPKVREPQ KRMMLKIYEC IKNKRNLIVE APTGVGKTLG YLIPALYFAE
     RRKRVLILTE TIDQQVRIYE DLSSLRHNLK VAFLMGKSNF ICKSKGGKAN RLYCQLNKKC
     LYRPNKRPIC YCGTKKQPVN LGDKVIYYCP YCTCEYQKAK IESILADIVV MNNSMFYYAK
     EDIEAKRDID IIICDEAHKL ESSIRNTSTI IINPELPINR LKYMAIHYAP NILKKRLDIG
     DENFWEIIEK YLTSRGINID ICKETIIFDG ENLSSWKYKT ELAVLGAILD AYYQINNIKN
     KILRFNENEE IDREELRFEI DNKALIAIEL DFIHKKKLSD LYLLEFIENI KNLRYINENY
     VVYRSGNSLL CEPVFVSSHL KELYGNAVVI HCSATIGNLK MHALKTGLDK AEFLILESPF
     PKNRKKIIAL KDGVDMKYER KDREKANKNL LKILEAINGN SLVLFKSFED LDSFYKYLKR
     EITKTNIKNK NIHVYEQGMD GKEAKELKER FEKIGGILLA TGRFAEGVDI PGEALVGVVI
     DSLPFPVPTP LILREQKILE ERFKIRGVRD AHWRAFLMTS FDRMARTLVQ MIGRLIRTEN
     DYGVVVIQDK RFADWVGRVM REKGYLKDNY EVMSLDMAIK YIPKFMSQFK N