ID   Y945_MYCTO              Reviewed;         253 AA.
AC   P9WGR6; L0T7Z5; P71564;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 42.
DE   RecName: Full=Uncharacterized oxidoreductase MT0971;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=MT0971;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK45219.1; -; Genomic_DNA.
DR   PIR; G70715; G70715.
DR   RefSeq; WP_003898658.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WGR6; -.
DR   SMR; P9WGR6; -.
DR   EnsemblBacteria; AAK45219; AAK45219; MT0971.
DR   KEGG; mtc:MT0971; -.
DR   PATRIC; fig|83331.31.peg.1042; -.
DR   HOGENOM; CLU_010194_2_1_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..253
FT                   /note="Uncharacterized oxidoreductase MT0971"
FT                   /id="PRO_0000428315"
FT   ACT_SITE        159
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         145
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   253 AA;  27139 MW;  BAD937208842DA12 CRC64;
     MLTGVTRQKI LITGASSGLG AGMARSFAAQ GRDLALCARR TDRLTELKAE LSQRYPDIKI
     AVAELDVNDH ERVPKVFAEL SDEIGGIDRV IVNAGIGKGA RLGSGKLWAN KATIETNLVA
     ALVQIETALD MFNQRGSGHL VLISSVLGVK GVPGVKAAYA ASKAGVRSLG ESLRAEYAQR
     PIRVTVLEPG YIESEMTAKS ASTMLMVDNA TGVKALVAAI EREPGRAAVP WWPWAPLVRL
     MWVLPPRLTR RFA