ID   Y946_ARCFU              Reviewed;        1036 AA.
AC   O29316;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Uncharacterized protein AF_0946;
DE   Flags: Precursor;
GN   OrderedLocusNames=AF_0946;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000782; AAB90312.1; -; Genomic_DNA.
DR   PIR; B69368; B69368.
DR   RefSeq; WP_010878446.1; NC_000917.1.
DR   AlphaFoldDB; O29316; -.
DR   STRING; 224325.AF_0946; -.
DR   EnsemblBacteria; AAB90312; AAB90312; AF_0946.
DR   GeneID; 63606521; -.
DR   KEGG; afu:AF_0946; -.
DR   eggNOG; arCOG06913; Archaea.
DR   HOGENOM; CLU_321509_0_0_2; -.
DR   OMA; THWINIT; -.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR026371; PGF_CTERM.
DR   TIGRFAMs; TIGR04126; PGF_CTERM; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..1036
FT                   /note="Uncharacterized protein AF_0946"
FT                   /id="PRO_0000013648"
FT   TRANSMEM        1011..1033
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1036 AA;  112426 MW;  CA9FCE0932F9899F CRC64;
     MKRVGLIGVI MAALLVISAT PVMAGVSVKV SVNTTYPGEL TVENFNLTPT YGRVPLTINI
     TDVYLKNTNL TTPLSGTVYL YVNGQIKNNY YCSVTQTNNT TSWMSCGIEY TITDTSQTNI
     SVGNKTDYLQ NVTLTLWTTQ LPESYVPQIP TLDLKDDGPI SVDVLKIPSL KLSDDQVNVG
     ETVTIEANWN YYAKEDGTRR IAVVSWADYR NIRSGATIDV ATLLDKSKMT ISLPEDGGSN
     SWDFTPTEPG YYVVVAFVDD TNFSDVLVFR ATPTAAEKPT VSISVSKSVV ALGDYIKVGA
     SMSTDQAVKP IAVFITGANQ TEVLCSYPEP GASTVGAWTV KEACGDDEWW IQIKDRPEGV
     YVAKIDVGEG ELRAEATAVF QVVKPKILSL DVPSQHVKGQ DLVITGTTNL AKSGTEDDSG
     SNAAENKAYL VIKDLSGKEV FNDTLSNQVY DSTGGKVKSN AVSLIDSDGS FKFKIDYFGK
     YFATETGFYI AEVKIQSDSL GEYTDTETAT FEVVKPELKL IADKTTVTRG DTVTFTIDTN
     LKINSEVKFK IDDLAFCSGD PDCDVKEKTY YVDALGDVVI KLDVNTEAPL TDYKFTAEIP
     GLGISTDIRV SVVKQTLDIS VDRTTVPRGG DIRVTGSSTA DGVYIYASDS GVFTVGDTPV
     PDVDLKTKGS KINTTDVPYM EPDDNDNIDF QISVNVTGVE TGTYYLYFYA PANISVVDKA
     SDPQKIIAVT VTDPQIVEVT APSKVPYQSK FEVSVLTDPG DRDNVEVRLV LSGPNVRDTT
     VADWASVDTN NYFNKTVDLR DIAKNKLNLD ALEPGLYVLT AELRFKQSLG GEKVDSEDKL
     IEILGLTFEV DVNTPVVIGD EIVVNITTDR LEAGYDKIFV TLVGTNYKVT QVATLNSEGK
     ATVTFETYGM SAGTYKVYVR DTMDTCSETD QYTWVDEHYM LDPASELAPM YKADDDVLVI
     KTIELLETAP TTTTVVTTTT AVTTTTVATT TTAVETTTTE AVTTTTEAQQ GGGVPGFEAV
     FAIAGLLAVA YLLRRK