Y952_HAEIN
ID Y952_HAEIN Reviewed; 221 AA.
AC P44952;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 14-NOV-2003, sequence version 2.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=UPF0758 protein HI_0952;
GN OrderedLocusNames=HI_0952;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- SIMILARITY: Belongs to the UPF0758 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC22613.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; L42023; AAC22613.1; ALT_INIT; Genomic_DNA.
DR PIR; F64104; F64104.
DR RefSeq; NP_439113.2; NC_000907.1.
DR RefSeq; WP_010869094.1; NC_000907.1.
DR AlphaFoldDB; P44952; -.
DR SMR; P44952; -.
DR STRING; 71421.HI_0952; -.
DR EnsemblBacteria; AAC22613; AAC22613; HI_0952.
DR KEGG; hin:HI_0952; -.
DR PATRIC; fig|71421.8.peg.994; -.
DR eggNOG; COG2003; Bacteria.
DR HOGENOM; CLU_073529_0_2_6; -.
DR PhylomeDB; P44952; -.
DR BioCyc; HINF71421:G1GJ1-993-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd08071; MPN_DUF2466; 1.
DR InterPro; IPR037518; MPN.
DR InterPro; IPR025657; RadC_JAB.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR001405; UPF0758.
DR InterPro; IPR020891; UPF0758_CS.
DR PANTHER; PTHR30471; PTHR30471; 1.
DR Pfam; PF04002; RadC; 1.
DR SUPFAM; SSF47781; SSF47781; 1.
DR TIGRFAMs; TIGR00608; radc; 1.
DR PROSITE; PS50249; MPN; 1.
DR PROSITE; PS01302; UPF0758; 1.
PE 3: Inferred from homology;
KW Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome;
KW Zinc.
FT CHAIN 1..221
FT /note="UPF0758 protein HI_0952"
FT /id="PRO_0000190703"
FT DOMAIN 99..221
FT /note="MPN"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT MOTIF 170..183
FT /note="JAMM motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 170
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 172
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 183
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
SQ SEQUENCE 221 AA; 25028 MW; D76ACEF7BB8ED605 CRC64;
MENNDELMPR EKLLAFGAKA LSDYELLAIF LRTGIKGCPV MSLSKNVLTH FGPLHALLSA
DKKAFCSVKG LGITQFIQLQ AITEMTKRYL KQDMLSTPII NDPETVKLFL LTELQHEERE
VFMVLFLDNQ HRLIKKERLF LGTIYVSAVY PREIIKEALY CNAAALILAH NHPSGITEPS
YSDQLITKKI QDAAELMEIR VLDHLIVGKS DCYSFAENCL L
