ID   Y955_MYCMM              Reviewed;         313 AA.
AC   B2HSF4;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MMAR_0955;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MMAR_0955;
OS   Mycobacterium marinum (strain ATCC BAA-535 / M).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=216594;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-535 / M;
RX   PubMed=18403782; DOI=10.1101/gr.075069.107;
RA   Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K.,
RA   Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C.,
RA   Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K.,
RA   Lord A., Moule S., Mungall K., Norbertczak H., Quail M.A.,
RA   Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R.,
RA   Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T.;
RT   "Insights from the complete genome sequence of Mycobacterium marinum on the
RT   evolution of Mycobacterium tuberculosis.";
RL   Genome Res. 18:729-741(2008).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000854; ACC39412.1; -; Genomic_DNA.
DR   RefSeq; WP_012392874.1; NC_010612.1.
DR   AlphaFoldDB; B2HSF4; -.
DR   SMR; B2HSF4; -.
DR   STRING; 216594.MMAR_0955; -.
DR   EnsemblBacteria; ACC39412; ACC39412; MMAR_0955.
DR   GeneID; 64259692; -.
DR   KEGG; mmi:MMAR_0955; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; NDTWEIT; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001190; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..313
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MMAR_0955"
FT                   /id="PRO_0000361175"
FT   BINDING         132
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         161..162
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   313 AA;  34681 MW;  887E76B1571BD4F4 CRC64;
     MARTEDDSWE ITESVGATAL GVASARAAET RSQHPLISDP FAQVFLDAVG DGVWNWHSAP
     QLPAELLEIE PDLPLQMEAM VSYMASRTAF FDEFFLDATR AGIGQAVILA AGLDSRAWRL
     PWPAGTTVFE LDQPRVLEFK AATLAEHGAE PACGRVAVAV DLRQDWPTAL RQAGFDPSVP
     SVWSAEGLMP YLPAVAQDLL FERVQGLTVR ASRIAVEALG PKFLDPQVRA NRSARMERIR
     AVMAHVEPQR EIPRTDELWY FEEREDVGDW FRRHDWDVTV TPSGELMAGY GRAAAAQVED
     RVPTNLFVAA QRK