ID   Y9625_DICDI             Reviewed;        1256 AA.
AC   Q54DK0;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Putative protein DDB_G0292252;
GN   ORFNames=DDB_G0292252;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000188; EAL61336.1; -; Genomic_DNA.
DR   RefSeq; XP_629727.1; XM_629725.1.
DR   AlphaFoldDB; Q54DK0; -.
DR   SMR; Q54DK0; -.
DR   STRING; 44689.DDB0302367; -.
DR   PaxDb; Q54DK0; -.
DR   EnsemblProtists; EAL61336; EAL61336; DDB_G0292252.
DR   GeneID; 8628555; -.
DR   KEGG; ddi:DDB_G0292252; -.
DR   dictyBase; DDB_G0292252; -.
DR   eggNOG; ENOG502SGIE; Eukaryota.
DR   HOGENOM; CLU_265322_0_0_1; -.
DR   InParanoid; Q54DK0; -.
DR   OMA; THNVFWD; -.
DR   Reactome; R-DDI-114604; GPVI-mediated activation cascade.
DR   Reactome; R-DDI-1660499; Synthesis of PIPs at the plasma membrane.
DR   Reactome; R-DDI-392451; G beta:gamma signalling through PI3Kgamma.
DR   PRO; PR:Q54DK0; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   GO; GO:0005942; C:phosphatidylinositol 3-kinase complex; IBA:GO_Central.
DR   GO; GO:0005944; C:phosphatidylinositol 3-kinase complex, class IB; IEA:InterPro.
DR   GO; GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IBA:GO_Central.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0043406; P:positive regulation of MAP kinase activity; IBA:GO_Central.
DR   InterPro; IPR019522; PIK3R5/6.
DR   PANTHER; PTHR15593; PTHR15593; 1.
DR   Pfam; PF10486; PI3K_1B_p101; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..1256
FT                   /note="Putative protein DDB_G0292252"
FT                   /id="PRO_0000344385"
FT   REGION          1..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          145..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          898..951
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1069..1136
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1256 AA;  141715 MW;  04F498CBED7C9E9D CRC64;
     MSDDNNSNNM SNNNNNNNNN NNNNNNNNNN NNNNNNNNSN NNNSNNNNEN NNNKSFQIQP
     ILIQISEILQ QSIELKLCSS VNTHNVFWDT LLYNLELNGD AISMIISLLL TKYILLLNNE
     NNQYSLLQAL FTKLTNASVE EFNDLLNGNN SNNNSNNNNN NNNNNNNNNN NNNNNNNNNN
     NNNNNNNNNN NNNNNNNNNN NNNSNGNNIN TSNGNEDDVE QQTESTEQDF TSTSQNSTPS
     ISRLASKLSQ TDLDSFNLSI SETNLTGVNY SSVSPQQSSP PLISTSSTGS LSNDYININN
     NNNSNSNINI NTSGTNDSDS TTTFSINGIN MSSEEIKESE TIRLSILSTI GYLSLFHKFN
     PQFPTLKVII HKLGEIQLEK SRFEYSLHNE VLRILQTNNQ DNNDFLFFLI DQCSDQNSSN
     LDNLKLNNNI NKINSWYNPS IRKILREESV SKSKAVFEHL LLFLKHPLLS EKRVLFLLQM
     LKHYLLVIPV LSSLTIQSAL SIVKTYYLWP KPYGCFAKEI LEILSLELKS PGSYFRNILA
     REFPSIMSSP NSIGSASLTN TLFTNKNRPT IHFLVDKYNS EALLIQELFE ANYNTYTPSI
     TQLQSNNIEN IYKRILGIDN SQLGIEFLEP IDVSTIHFKI LDVMNKTMYL EENESKSIRI
     KELISIRDEI IKFCNLSTNS NSNLNSTTTT ATTTNILKHV PKNIELPNLN YQFISMLTLS
     VRHKRPDQFG TPFYIPINRK STTSLIDLLS NYQDQDFHNQ VKFAIIGNDT SVQHILASYL
     FLKYQQPELF HSLDIMFYII PTGTSNCKIA ELISSFDPWY TNQVRQCLVS LYSIIPSFPP
     ISKLSKIERQ SFIESISQIK DLRNSIALKE NELEQQQQQQ PQQPQQQNSD VASIILNEQQ
     QQQQQQQSNL NNSNNEIKND INSSTTAATT TTTTTTTTTT TTIHKDNPVE TPSHTIQTEI
     EYLFREASFS LEIPVLKCEG WGIDDNNYFT IPFLMKAEMN TSTFLAGFSD LISSDPTQIN
     KLMGKYSPMN VNIKILQCNQ MGVPLQWINI DNKTFYDIEI NNIMPKSISH PTIQSTSSPS
     TSSSNNNNST TTATNNNGNN GNNNNGNGNN NNNNNNNNNN NNNNNNNNNN GPATISSSLK
     KSIIQSKPKM QLVLIEAEQK KKKVKSSEDT FKFTINAIEM ESIDKKKSFD ILLDGQLHGP
     FNKIKISFCS SNISNIINNA AKNSSSSNSS NYSIGFNDLQ DNDFITFPIM SFLPLV