ID   Y9645_CAMJU             Reviewed;         264 AA.
AC   Q4VR96;
DT   17-JUN-2020, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Probable nucleotidyltransferase {ECO:0000305};
DE            EC=2.7.7.-;
DE   AltName: Full=ORF11 {ECO:0000303|PubMed:15917546};
GN   Name=aadA {ECO:0000303|PubMed:15917546}; ORFNames=C9J79_09645;
OS   Campylobacter jejuni.
OG   Plasmid pCG8245, and Plasmid pGMI16-002.
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Campylobacteraceae; Campylobacter.
OX   NCBI_TaxID=197;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], LACK OF FUNCTION ON SPECTINOMYCIN OR
RP   STREPTOMYIN, AND DISRUPTION PHENOTYPE.
RC   STRAIN=CG8245 / Serotype Lior 19; PLASMID=pCG8245;
RX   PubMed=15917546; DOI=10.1128/aac.49.6.2454-2459.2005;
RA   Nirdnoy W., Mason C.J., Guerry P.;
RT   "Mosaic structure of a multiple-drug-resistant, conjugative plasmid from
RT   Campylobacter jejuni.";
RL   Antimicrob. Agents Chemother. 49:2454-2459(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFSAN054107; PLASMID=pGMI16-002;
RA   Hoffmann M., Pedersen S.K., Sanchez M., Pettengill J.B., Hendriksen R.S.;
RT   "Genome assemblies for Global Microbial Identifier (GMI) Proficiency
RT   Testing reference strains.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probably a nucleotidyltransferase, it does not confer
CC       spectinomycin or streptomyin resistance in situ or in E.coli.
CC       {ECO:0000269|PubMed:15917546}.
CC   -!- DISRUPTION PHENOTYPE: No change in spectinomycin or streptomycin
CC       resistance. {ECO:0000269|PubMed:15917546}.
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DR   EMBL; AY701528; AAW34148.1; -; Genomic_DNA.
DR   EMBL; CP028186; AVS37847.1; -; Genomic_DNA.
DR   RefSeq; WP_021424055.1; NZ_CP028186.1.
DR   AlphaFoldDB; Q4VR96; -.
DR   SMR; Q4VR96; -.
DR   EnsemblBacteria; AVS37847; AVS37847; C9J79_09645.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR025184; DUF4111.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR   Pfam; PF13427; DUF4111; 1.
DR   Pfam; PF01909; NTP_transf_2; 1.
DR   SUPFAM; SSF81301; SSF81301; 1.
PE   4: Predicted;
KW   Plasmid; Transferase.
FT   CHAIN           1..264
FT                   /note="Probable nucleotidyltransferase"
FT                   /id="PRO_0000450273"
SQ   SEQUENCE   264 AA;  31003 MW;  B4FB31D9168DDEE8 CRC64;
     MVVQMDIYDL MKQVNEWVKE ILQDNYVGVY FHGSLRLGSF NPNKSDLDFI IVVKEKIDNE
     IKQLIWDKML ENEQLFPKKG FEFSVVLEDN CRNIKHPIPY ELHGSRDWIE RYKEDKTIVI
     NDDYKVDPDL ASHFNVINVP NDKMDFGKPS KEVFSKVPKE YIIDSNYSDT LDCVEEIVNN
     PVYCILNLCR FYALIRDDLT LSKYDGGKWA LENMNSNYND VIKNAMEDYL SDTNNSYDNT
     RLKEFAQEAI SLINDCVDTN KIRK