ID   Y966_METJA              Reviewed;         444 AA.
AC   Q58376;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Uncharacterized protein MJ0966;
GN   OrderedLocusNames=MJ0966;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000305};
CC       Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3
CC       cysteines and an exchangeable S-adenosyl-L-methionine. {ECO:0000305};
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DR   EMBL; L77117; AAB98968.1; -; Genomic_DNA.
DR   PIR; F64420; F64420.
DR   AlphaFoldDB; Q58376; -.
DR   SMR; Q58376; -.
DR   STRING; 243232.MJ_0966; -.
DR   EnsemblBacteria; AAB98968; AAB98968; MJ_0966.
DR   KEGG; mja:MJ_0966; -.
DR   eggNOG; arCOG01355; Archaea.
DR   HOGENOM; CLU_011543_3_3_2; -.
DR   InParanoid; Q58376; -.
DR   OMA; PESYNWS; -.
DR   PhylomeDB; Q58376; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.30.20; -; 1.
DR   InterPro; IPR006638; Elp3/MiaB/NifB.
DR   InterPro; IPR045784; Radical_SAM_N2.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR023404; rSAM_horseshoe.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   Pfam; PF19864; Radical_SAM_N2; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SMART; SM00729; Elp3; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   4: Predicted;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome;
KW   S-adenosyl-L-methionine.
FT   CHAIN           1..444
FT                   /note="Uncharacterized protein MJ0966"
FT                   /id="PRO_0000107122"
FT   DOMAIN          164..381
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         178
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
FT   BINDING         182
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
FT   BINDING         185
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   444 AA;  51348 MW;  25ABAB5890A20C70 CRC64;
     MIKMIKNVAI IYPNKFKAGI SCLAVHVLAN HLSKYRDLNV GVYFLENYDR IKNFDAIFIT
     LQYENDYFNA IKIIKDLRKN NPNAIFVAGG PCVMENFFPI AEFFDVFIVG EIEGSDVMLK
     VINREFDVEG VYSKYLEKDK VKRIYPKKLT IDDYPIYQPT SEEGAYGKSF LLEIGRGCPR
     RCRFCLARAI YYPPRFRKLD DLMYLAEEGV KVNKVNKVAL IAPSVGDYKY IVELCNFLDD
     MGVHISPSSL RADTLNDDLM RILKPKTLTI APEAGSERLR EFIKKDIRER DIANAIDLAK
     KFGVEKVKLY FMVGIPTETD EDIEELINLT KKVKKEIRKV EISVNPMIPK PHTDFEVEEF
     DLSSKKKIKY IEKALKKEGI RVEYENFNSM ICQCILARGD ENLSKYLDYS KNPTSLISAL
     KKDRLLDKYL GRFEDKGVWK NIIL