ID   Y966_MYCTU              Reviewed;         200 AA.
AC   P9WKM1; L0T5B3; P71544;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Uncharacterized protein Rv0966c;
GN   OrderedLocusNames=Rv0966c; ORFNames=MTCY10D7.08;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   INDUCTION.
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=16586367; DOI=10.1086/502631;
RA   Jain S.K., Paul-Satyaseela M., Lamichhane G., Kim K.S., Bishai W.R.;
RT   "Mycobacterium tuberculosis invasion and traversal across an in vitro human
RT   blood-brain barrier as a pathogenic mechanism for central nervous system
RT   tuberculosis.";
RL   J. Infect. Dis. 193:1287-1295(2006).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- INDUCTION: Highly up-regulated during the early stages of invasion of
CC       the human blood-brain barrier. {ECO:0000269|PubMed:16586367}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL123456; CCP43715.1; -; Genomic_DNA.
DR   PIR; D70718; D70718.
DR   RefSeq; NP_215481.2; NC_000962.3.
DR   RefSeq; WP_010886096.1; NZ_NVQJ01000001.1.
DR   AlphaFoldDB; P9WKM1; -.
DR   SMR; P9WKM1; -.
DR   STRING; 83332.Rv0966c; -.
DR   PaxDb; P9WKM1; -.
DR   DNASU; 885043; -.
DR   GeneID; 885043; -.
DR   KEGG; mtu:Rv0966c; -.
DR   TubercuList; Rv0966c; -.
DR   eggNOG; COG4758; Bacteria.
DR   OMA; FAFWGGG; -.
DR   PhylomeDB; P9WKM1; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   InterPro; IPR012551; DUF1707.
DR   Pfam; PF08044; DUF1707; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..200
FT                   /note="Uncharacterized protein Rv0966c"
FT                   /id="PRO_0000103764"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   200 AA;  22210 MW;  752F8CFBE9BB3C02 CRC64;
     MSNSAQRDAR NSRDESARAS DTDRIQIAQL LAYAAEQGRL QLTDYEDRLA RAYAATTYQE
     LDRLRADLPG AAIGPRRGGE CNPAPSTLLL ALLGGFERRG RWNVPKKLTT FTLWGSGVLD
     LRYADFTSTE VDIRAYSIMG AQTILLPPEV NVEIHGHRVM GGFDRKVVGE GTRGVPTVRI
     RGFSLWGDVG IKRKPRKPRK