ID   Y967_METTH              Reviewed;         311 AA.
AC   O27048;
DT   25-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 117.
DE   RecName: Full=Putative HTH-type transcriptional regulatory protein MTH_967 {ECO:0000255|HAMAP-Rule:MF_00584};
GN   OrderedLocusNames=MTH_967;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
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DR   EMBL; AE000666; AAB85463.1; -; Genomic_DNA.
DR   PIR; D69229; D69229.
DR   RefSeq; WP_010876598.1; NC_000916.1.
DR   AlphaFoldDB; O27048; -.
DR   SMR; O27048; -.
DR   STRING; 187420.MTH_967; -.
DR   EnsemblBacteria; AAB85463; AAB85463; MTH_967.
DR   GeneID; 1471375; -.
DR   KEGG; mth:MTH_967; -.
DR   PATRIC; fig|187420.15.peg.950; -.
DR   HOGENOM; CLU_075726_0_0_2; -.
DR   OMA; PGVVYFR; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   HAMAP; MF_00584; HTH_type_cro_C1; 1.
DR   InterPro; IPR020886; Arc_TR_HTH.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..311
FT                   /note="Putative HTH-type transcriptional regulatory protein
FT                   MTH_967"
FT                   /id="PRO_0000144859"
FT   DOMAIN          134..192
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
FT   DNA_BIND        145..164
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00584"
SQ   SEQUENCE   311 AA;  35357 MW;  B51C71F49848301B CRC64;
     MDKSIKREHV LREIHELLAS NGFETSHIYE RSCFDLMARR KLLLLLLKVL VNIDGINSLQ
     AHEIRTLAHT FLASPIIVGV RSKTEPLKED VVYERHGIPA VAPETFRNMV ADGEYPEIIA
     DRGGYYVHID GKTLREVREE YNLSLKDLAD LAHVSRKTIY KYENGLARAS AETAMILEEI
     LNIRITLSID IFSVPDRDEI EIKPSGRLAD IGFGMIETHK TPFDAVAKEI KFDNTVITNL
     EKERDSRTLR RMAVPLKDLS LVSGSESVFI IDNPRINENI EGIPVIKSWE IGEMESSREF
     LKVIAERKTC S