ID   Y971_METJA              Reviewed;         365 AA.
AC   Q58381;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Uncharacterized protein MJ0971;
GN   OrderedLocusNames=MJ0971;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To S.solfataricus C04034. {ECO:0000305}.
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DR   EMBL; L77117; AAB98976.1; -; Genomic_DNA.
DR   PIR; C64421; C64421.
DR   AlphaFoldDB; Q58381; -.
DR   STRING; 243232.MJ_0971; -.
DR   EnsemblBacteria; AAB98976; AAB98976; MJ_0971.
DR   KEGG; mja:MJ_0971; -.
DR   eggNOG; arCOG04064; Archaea.
DR   HOGENOM; CLU_042134_1_0_2; -.
DR   InParanoid; Q58381; -.
DR   OMA; TIPLWYG; -.
DR   PhylomeDB; Q58381; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IBA:GO_Central.
DR   GO; GO:0031293; P:membrane protein intracellular domain proteolysis; IBA:GO_Central.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR001193; MBTPS2.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR008915; Peptidase_M50.
DR   PANTHER; PTHR13325; PTHR13325; 2.
DR   Pfam; PF13180; PDZ_2; 1.
DR   Pfam; PF02163; Peptidase_M50; 1.
DR   PRINTS; PR01000; SREBPS2PTASE.
DR   SUPFAM; SSF50156; SSF50156; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..365
FT                   /note="Uncharacterized protein MJ0971"
FT                   /id="PRO_0000107124"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        171..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        280..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   365 AA;  41082 MW;  F1608E3149691942 CRC64;
     MNMDTSKVIL IVAIIIWIIL YSIRDSINLK TYGGIFGILR TKLGLKTIEK LGKYKIWQKI
     GIISIPICVI LGFFMLLNII DMSIRLLSGT LPKEAAKPVV FLFGDVIPWI PGIIALLIAI
     SVHELAHGIF AKSFGIKVKS SGILLLLGLP LGAFVELGDE FKTADKKIRG AIASAGPLAN
     LIIFLTSIPL LSFSYTLPTE LKIIDVKEPA SEFLQKGDII YEINGKKINS LEDFKEFAKT
     IEPKKEYEIK ILRDNKILTY KIVSSNEGKL GIMVSPTKNT ALFINTIYWT YWFNFLLALF
     NLLPAMPLDG FHVWNAFPEL LKERKNRFIS KVGQILELFI NEKTLGSITL LVWWVILGSI
     LYSMW