ID   Y972_METJA              Reviewed;         228 AA.
AC   Q58382;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=UPF0056 membrane protein MJ0972;
GN   OrderedLocusNames=MJ0972;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0056 (MarC) family. {ECO:0000305}.
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DR   EMBL; L77117; AAB98977.1; -; Genomic_DNA.
DR   PIR; D64421; D64421.
DR   AlphaFoldDB; Q58382; -.
DR   STRING; 243232.MJ_0972; -.
DR   EnsemblBacteria; AAB98977; AAB98977; MJ_0972.
DR   KEGG; mja:MJ_0972; -.
DR   eggNOG; arCOG01997; Archaea.
DR   HOGENOM; CLU_079909_1_0_2; -.
DR   InParanoid; Q58382; -.
DR   OMA; MMAIVML; -.
DR   PhylomeDB; Q58382; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002771; Multi_antbiot-R_MarC.
DR   PANTHER; PTHR33508; PTHR33508; 1.
DR   Pfam; PF01914; MarC; 1.
DR   TIGRFAMs; TIGR00427; TIGR00427; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..228
FT                   /note="UPF0056 membrane protein MJ0972"
FT                   /id="PRO_0000156917"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   228 AA;  25360 MW;  D259B7E8C5F38D6E CRC64;
     MVGYSGEHFI FNVVKYMDIL NFYIYGFVSL FITIDPIGLI PIVHSLTYPY PKEQRIRIIK
     KAIISSTVVL LLFALFGNYI FGYFGITIDA FRVAGGILLF KIAWDMLHAE IPKTKHKPDE
     RLDLEDIDSI VYVPLAIPLI SGPGAITTTM ILISKTQSIL EKGVVVLSIL SAMLVSGIIL
     SLTDFIIRRV NIYGINAFVR IMGLLLVAIS VQIIFTGIVG LYNSISVQ