ID   Y976_TREPA              Reviewed;         459 AA.
AC   O83941;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Uncharacterized protein TP_0976;
GN   OrderedLocusNames=TP_0976;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65940.1; -; Genomic_DNA.
DR   PIR; F71257; F71257.
DR   RefSeq; WP_010882420.1; NC_021490.2.
DR   AlphaFoldDB; O83941; -.
DR   IntAct; O83941; 6.
DR   STRING; 243276.TPANIC_0976; -.
DR   EnsemblBacteria; AAC65940; AAC65940; TP_0976.
DR   GeneID; 57879485; -.
DR   KEGG; tpa:TP_0976; -.
DR   eggNOG; ENOG5030273; Bacteria.
DR   HOGENOM; CLU_555407_0_0_12; -.
DR   OMA; SAHEMML; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..459
FT                   /note="Uncharacterized protein TP_0976"
FT                   /id="PRO_0000202368"
FT   TRANSMEM        53..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        111..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          174..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   459 AA;  49188 MW;  AB54E7F5BCB4D3BF CRC64;
     MVLTQKNLVK RTTESTETEA VSDLLVSELL ILGLSLPALL RPFSRQSRKI SAIPLLPVLA
     LSVGALTVLG QGLTLDLTLS LVSSSVVCLT ELPRLVAFSQ GIPNDLYSAG ARIARVLLLV
     AGVFTLVIVC LCAPEPGYRP SRSVVRSSFS LRLGNTKVNA GLLLSLANPY ETSHLDNPSA
     PHPSENPQSR AHPKQNPVGV NVVVLKNTPQ SAHRAHPETL ELMLAERGYT VFVPYQDAYS
     PSYSAASLAA PMRTSPGVVL LSSALRGVPF DVPTPYVSRR ANTIDAATFE DAHVPALFPA
     LFALCRHAPT FVYAESAHEV MLSRFLQQQP HACAGVFFVL PDSAARGPHH APAVQGAPPP
     VDTAGVASAV RGASRTLPAV YRQYVHAAEA AWAELASTDI LAAYLAGLPR DRHRTRLQAR
     ATQVDQWIRA QLHLSEPVLP HAQALSHHTV HAGGTYDRT