ID   YA043_HUMAN             Reviewed;         218 AA.
AC   Q7L0L9;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 2.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Transmembrane protein LOC653160;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC021230; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; BC042172; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; Q7L0L9; -.
DR   SMR; Q7L0L9; -.
DR   BioMuta; -; -.
DR   DMDM; 261260085; -.
DR   PeptideAtlas; Q7L0L9; -.
DR   PRIDE; Q7L0L9; -.
DR   neXtProt; NX_Q7L0L9; -.
DR   Pharos; Q7L0L9; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q7L0L9; protein.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IBA:GO_Central.
DR   GO; GO:0051482; P:positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway; IBA:GO_Central.
DR   GO; GO:0035025; P:positive regulation of Rho protein signal transduction; IBA:GO_Central.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..218
FT                   /note="Transmembrane protein LOC653160"
FT                   /id="PRO_0000344452"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          18..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          196..218
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        202..218
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   218 AA;  23184 MW;  AA1840C63C48EB2C CRC64;
     MKGLRVAKAF QPSQGCSRQA LGHLSGRGPS PRSEMNSSVG DLGVGGCSLW DDPARFIVVP
     AAYALALGLG LPANVAALAM FIRSGGRLGQ ALLLYLFNLA LVDEFFTLTL QLWLTYYLGL
     ARRPPATRPG PPTTCPPMRR WSSPRSSACA AAASYAVPGP GRLPAWPGAY GAPRALPAPS
     PGWRAWPLPA WSTAGQARGW PPPRWPSRPP SCWCSRPT