YA066_YEAST
ID YA066_YEAST Reviewed; 203 AA.
AC P0CX18; D3DLG5; P38897; Q7LII8;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 57.
DE RecName: Full=Putative GPI-anchored protein YAR066W;
DE Flags: Precursor;
GN OrderedLocusNames=YAR066W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204511 / S288c / AB972;
RA Bussey H., Keng T., Storms R.K., Vo D., Zhong W., Fortin N., Barton A.B.,
RA Kaback D.B., Clark M.W.;
RT "Sequencing of chromosome I of Saccharomyces cerevisiae: analysis of the 52
RT Kbp CDC15-FLO1-PHO11-YAR074 region.";
RL Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7731988; DOI=10.1073/pnas.92.9.3809;
RA Bussey H., Kaback D.B., Zhong W.-W., Vo D.H., Clark M.W., Fortin N.,
RA Hall J., Ouellette B.F.F., Keng T., Barton A.B., Su Y., Davies C.J.,
RA Storms R.K.;
RT "The nucleotide sequence of chromosome I from Saccharomyces cerevisiae.";
RL Proc. Natl. Acad. Sci. U.S.A. 92:3809-3813(1995).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP PREDICTION OF GPI-ANCHOR.
RX PubMed=12845604; DOI=10.1002/yea.1007;
RA De Groot P.W., Hellingwerf K.J., Klis F.M.;
RT "Genome-wide identification of fungal GPI proteins.";
RL Yeast 20:781-796(2003).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC anchor {ECO:0000305}.
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DR EMBL; L28920; AAC09510.1; -; Genomic_DNA.
DR EMBL; AY692573; AAT92592.1; -; Genomic_DNA.
DR EMBL; BK006935; DAA07009.1; -; Genomic_DNA.
DR PIR; S48995; S48995.
DR RefSeq; NP_009430.1; NM_001180045.1.
DR RefSeq; NP_012084.3; NM_001179345.3.
DR AlphaFoldDB; P0CX18; -.
DR SMR; P0CX18; -.
DR BioGRID; 31817; 56.
DR BioGRID; 36647; 1.
DR PaxDb; P0CX18; -.
DR EnsemblFungi; YAR066W_mRNA; YAR066W; YAR066W.
DR EnsemblFungi; YHR214W_mRNA; YHR214W; YHR214W.
DR GeneID; 851295; -.
DR GeneID; 856621; -.
DR KEGG; sce:YAR066W; -.
DR KEGG; sce:YHR214W; -.
DR SGD; S000002144; YAR066W.
DR VEuPathDB; FungiDB:YAR066W; -.
DR VEuPathDB; FungiDB:YHR214W; -.
DR HOGENOM; CLU_077759_1_0_1; -.
DR OMA; QSXSSXS; -.
DR BioCyc; YEAST:G3O-28895-MON; -.
DR PRO; PR:P0CX18; -.
DR Proteomes; UP000002311; Chromosome I.
DR RNAct; P0CX18; protein.
DR ExpressionAtlas; P0CX18; baseline and differential.
DR GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane;
KW Reference proteome; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..184
FT /note="Putative GPI-anchored protein YAR066W"
FT /id="PRO_0000202945"
FT PROPEP 185..203
FT /note="Removed in mature form"
FT /evidence="ECO:0000255"
FT /id="PRO_0000409753"
FT LIPID 184
FT /note="GPI-anchor amidated asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 28
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 138
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 203 AA; 20594 MW; 466EC45BEECCC69C CRC64;
MFNRFNKFQA AVALALLSRG ALGDSYTNST SSADLSSITS VSSASASATA SDSLSSSDGT
VYLPSTTISG DLTVTGKVIA TEAVEVAAGG KLTLLDGEKY VFSSDLKVHG DLVVEKSEAS
YEGTAFDVSG ETFEVSGNFS AEETGAVSAS IYSFTPSSFK SSGDISLSLS KAKKGEVTFS
PYSNAGTFSL SNAILNGGSV SGL