ID   YA280_ASPFU             Reviewed;         242 AA.
AC   Q4WCX9;
DT   11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Uncharacterized protein AFUA_6G02800;
DE   Flags: Precursor;
GN   ORFNames=AFUA_6G02800;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
RN   [2]
RP   PROTEIN SEQUENCE OF 21-27 AND 49-58, AND GPI-ANCHOR.
RX   PubMed=11545413;
RX   DOI=10.1002/1522-2683(200108)22:13<2812::aid-elps2812>3.0.co;2-q;
RA   Bruneau J.-M., Magnin T., Tagat E., Legrand R., Bernard M., Diaquin M.,
RA   Fudali C., Latge J.-P.;
RT   "Proteome analysis of Aspergillus fumigatus identifies
RT   glycosylphosphatidylinositol-anchored proteins associated to the cell wall
RT   biosynthesis.";
RL   Electrophoresis 22:2812-2823(2001).
RN   [3]
RP   STRUCTURE OF GPI-ANCHOR.
RX   PubMed=12626404; DOI=10.1093/glycob/cwg004;
RA   Fontaine T., Magnin T., Melhert A., Lamont D., Latge J.-P.,
RA   Ferguson M.A.J.;
RT   "Structures of the glycosylphosphatidylinositol membrane anchors from
RT   Aspergillus fumigatus membrane proteins.";
RL   Glycobiology 13:169-177(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor.
CC   -!- PTM: The GPI-like anchor contains a phosphoceramide lipid group. The
CC       anchor position has not been determined.
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DR   EMBL; AAHF01000012; EAL85759.1; -; Genomic_DNA.
DR   RefSeq; XP_747797.1; XM_742704.1.
DR   AlphaFoldDB; Q4WCX9; -.
DR   SMR; Q4WCX9; -.
DR   STRING; 746128.CADAFUBP00009280; -.
DR   EnsemblFungi; EAL85759; EAL85759; AFUA_6G02800.
DR   GeneID; 3505159; -.
DR   KEGG; afm:AFUA_6G02800; -.
DR   VEuPathDB; FungiDB:Afu6g02800; -.
DR   eggNOG; ENOG502S92W; Eukaryota.
DR   HOGENOM; CLU_070647_2_0_1; -.
DR   InParanoid; Q4WCX9; -.
DR   OMA; CKNNTGV; -.
DR   OrthoDB; 1372377at2759; -.
DR   Proteomes; UP000002530; Chromosome 6.
DR   GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009277; C:fungal-type cell wall; IDA:AspGD.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Cell membrane; Direct protein sequencing; Glycoprotein; GPI-anchor;
KW   Lipoprotein; Membrane; Reference proteome; Signal; Transferase.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..218
FT                   /note="Uncharacterized protein AFUA_6G02800"
FT                   /id="PRO_0000245564"
FT   PROPEP          219..242
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000245565"
FT   REGION          176..214
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           218
FT                   /note="GPI-like-anchor amidated alanine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        47
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        86
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        122
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        159
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        178
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   242 AA;  24608 MW;  EF16F1EEA27D5DB4 CRC64;
     MKFSPAYLLA FAPIVAAHFR LQYPTSRGFN ADTMANFPCG DLAQSSNRTQ VSLSSGSFPV
     ALRMGHDETA VEVLLALGND PGTNFNITLH PTFRIEGLGE FCLPNVVFDE SVLGTKITDG
     MNATLQVQSN GDPSGGLYAC ADIQFSTTAQ DEKPSSCTNN TGISAIAFTG AAAERNANES
     TADGQAQSGS SGSSSDSGSH SGHSSATQTS STTASSTAGA VALETAAWGI LGAAVVGGLA
     VL