ID   YA88_ENCCU              Reviewed;         306 AA.
AC   Q8SUE5;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Uncharacterized membrane protein ECU10_0880;
GN   OrderedLocusNames=ECU10_0880;
OS   Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=284813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GB-M1;
RX   PubMed=11719806; DOI=10.1038/35106579;
RA   Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA   Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA   Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA   Vivares C.P.;
RT   "Genome sequence and gene compaction of the eukaryote parasite
RT   Encephalitozoon cuniculi.";
RL   Nature 414:450-453(2001).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], DEVELOPMENTAL
RP   STAGE, AND SUBCELLULAR LOCATION.
RX   PubMed=16691553; DOI=10.1002/pmic.200500796;
RA   Brosson D., Kuhn L., Delbac F., Garin J., Vivares C.P., Texier C.;
RT   "Proteomic analysis of the eukaryotic parasite Encephalitozoon cuniculi
RT   (microsporidia): a reference map for proteins expressed in late sporogonial
RT   stages.";
RL   Proteomics 6:3625-3635(2006).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in late sporogonial stages.
CC       {ECO:0000269|PubMed:16691553}.
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DR   EMBL; AL590449; CAD25807.1; -; Genomic_DNA.
DR   RefSeq; NP_586203.1; NM_001042036.1.
DR   AlphaFoldDB; Q8SUE5; -.
DR   GeneID; 859852; -.
DR   KEGG; ecu:ECU10_0880; -.
DR   VEuPathDB; MicrosporidiaDB:ECU10_0880; -.
DR   HOGENOM; CLU_084270_0_0_1; -.
DR   InParanoid; Q8SUE5; -.
DR   OMA; DSMNDIY; -.
DR   OrthoDB; 1221371at2759; -.
DR   Proteomes; UP000000819; Chromosome X.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR000195; Rab-GTPase-TBC_dom.
DR   InterPro; IPR035969; Rab-GTPase_TBC_sf.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   SUPFAM; SSF47923; SSF47923; 1.
PE   1: Evidence at protein level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..306
FT                   /note="Uncharacterized membrane protein ECU10_0880"
FT                   /id="PRO_0000383035"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        208
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   306 AA;  35402 MW;  4AD0210E4F9785DF CRC64;
     MEGIKFADVL RSFEKKAEDD EYVSVERDYN ERKVIENDVR RTELLGVDKR NRKVIKVLKR
     LLFVELDKIP IKYTQGMSEI ASVFVLYYFQ NIVEEEVAKG VLASGSDEES AEESAADGFS
     EQFIEAPEDE NVELKRFVSR HKDTTAILGI VLTNVFRRKL EPLVVDDFKL YKENMRIFVE
     MMKKKGIRIP ELESYKFMGS ILTFFLRNLS RMEDVHKVFE IILSCPNTCP FLLLVLFYDK
     ISNGKTIDSI VNNDLFPKVV KLEEEFVETK KRVESRSGFS RMRVMLVGGI ASIVAAVVVY
     KITKKE