YAAJ_ECOLI
ID YAAJ_ECOLI Reviewed; 476 AA.
AC P30143;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1993, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Uncharacterized transporter YaaJ;
GN Name=yaaJ; OrderedLocusNames=b0007, JW0006;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=1630901; DOI=10.1093/nar/20.13.3305;
RA Yura T., Mori H., Nagai H., Nagata T., Ishihama A., Fujita N., Isono K.,
RA Mizobuchi K., Nakata A.;
RT "Systematic sequencing of the Escherichia coli genome: analysis of the 0-
RT 2.4 min region.";
RL Nucleic Acids Res. 20:3305-3308(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC (TC 2.A.25) family. {ECO:0000305}.
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DR EMBL; U00096; AAC73118.1; -; Genomic_DNA.
DR EMBL; AP009048; BAB96585.1; -; Genomic_DNA.
DR PIR; G64720; G64720.
DR RefSeq; NP_414548.1; NC_000913.3.
DR RefSeq; WP_001112606.1; NZ_LN832404.1.
DR AlphaFoldDB; P30143; -.
DR SMR; P30143; -.
DR BioGRID; 4261938; 470.
DR STRING; 511145.b0007; -.
DR TCDB; 2.A.25.1.10; the alanine or glycine:cation symporter (agcs) family.
DR PaxDb; P30143; -.
DR PRIDE; P30143; -.
DR EnsemblBacteria; AAC73118; AAC73118; b0007.
DR EnsemblBacteria; BAB96585; BAB96585; BAB96585.
DR GeneID; 66671701; -.
DR GeneID; 944745; -.
DR KEGG; ecj:JW0006; -.
DR KEGG; eco:b0007; -.
DR PATRIC; fig|1411691.4.peg.2276; -.
DR EchoBASE; EB1516; -.
DR eggNOG; COG1115; Bacteria.
DR HOGENOM; CLU_024867_0_1_6; -.
DR InParanoid; P30143; -.
DR OMA; PMMALFY; -.
DR PhylomeDB; P30143; -.
DR BioCyc; EcoCyc:YAAJ-MON; -.
DR PRO; PR:P30143; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0015655; F:alanine:sodium symporter activity; IEA:InterPro.
DR InterPro; IPR001463; Na/Ala_symport.
DR PANTHER; PTHR30330; PTHR30330; 1.
DR Pfam; PF01235; Na_Ala_symp; 1.
DR PRINTS; PR00175; NAALASMPORT.
DR TIGRFAMs; TIGR00835; agcS; 1.
DR PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome; Symport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..476
FT /note="Uncharacterized transporter YaaJ"
FT /id="PRO_0000161566"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 207..227
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 300..320
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 351..371
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 391..411
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 414..434
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 476 AA; 51663 MW; 2F6EB2E12E126E63 CRC64;
MPDFFSFINS VLWGSVMIYL LFGAGCWFTF RTGFVQFRYI RQFGKSLKNS IHPQPGGLTS
FQSLCTSLAA RVGSGNLAGV ALAITAGGPG AVFWMWVAAF IGMATSFAEC SLAQLYKERD
VNGQFRGGPA WYMARGLGMR WMGVLFAVFL LIAYGIIFSG VQANAVARAL SFSFDFPPLV
TGIILAVFTL LAITRGLHGV ARLMQGFVPL MAIIWVLTSL VICVMNIGQL PHVIWSIFES
AFGWQEAAGG AAGYTLSQAI TNGFQRSMFS NEAGMGSTPN AAAAAASWPP HPAAQGIVQM
IGIFIDTLVI CTASAMLILL AGNGTTYMPL EGIQLIQKAM RVLMGSWGAE FVTLVVILFA
FSSIVANYIY AENNLFFLRL NNPKAIWCLR ICTFATVIGG TLLSLPLMWQ LADIIMACMA
ITNLTAILLL SPVVHTIASD YLRQRKLGVR PVFDPLRYPD IGRQLSPDAW DDVSQE
