YAAT_BACSU
ID YAAT_BACSU Reviewed; 275 AA.
AC P37541;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Stage 0 sporulation protein YaaT;
GN Name=yaaT; OrderedLocusNames=BSU00320;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=7584024; DOI=10.1093/dnares/1.1.1;
RA Ogasawara N., Nakai S., Yoshikawa H.;
RT "Systematic sequencing of the 180 kilobase region of the Bacillus subtilis
RT chromosome containing the replication origin.";
RL DNA Res. 1:1-14(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP ROLE IN SPORULATION.
RC STRAIN=168;
RX PubMed=12270811; DOI=10.1128/jb.184.20.5545-5553.2002;
RA Hosoya S., Asai K., Ogasawara N., Takeuchi M., Sato T.;
RT "Mutation in yaaT leads to significant inhibition of phosphorelay during
RT sporulation in Bacillus subtilis.";
RL J. Bacteriol. 184:5545-5553(2002).
CC -!- FUNCTION: Essential for the phosphorelay during initiation of
CC sporulation. May control the level of phosphorylated spo0A through
CC spo0E activity during sporulation. {ECO:0000269|PubMed:12270811}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm. Note=In the vegetative phase,
CC localized throughout the periphery of the cell and the division septum.
CC In the sporulation stages, fluorescence of the YaaT-GFP fusion protein
CC was observed as two dots at the sides of an asymmetric septum and at
CC the edges of the forespore.
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DR EMBL; D26185; BAA05268.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB11808.1; -; Genomic_DNA.
DR PIR; S66062; S66062.
DR RefSeq; NP_387913.1; NC_000964.3.
DR RefSeq; WP_003243571.1; NZ_JNCM01000028.1.
DR AlphaFoldDB; P37541; -.
DR IntAct; P37541; 1.
DR STRING; 224308.BSU00320; -.
DR PaxDb; P37541; -.
DR PRIDE; P37541; -.
DR EnsemblBacteria; CAB11808; CAB11808; BSU_00320.
DR GeneID; 937012; -.
DR KEGG; bsu:BSU00320; -.
DR PATRIC; fig|224308.179.peg.32; -.
DR eggNOG; COG1774; Bacteria.
DR InParanoid; P37541; -.
DR OMA; YGGLGPC; -.
DR PhylomeDB; P37541; -.
DR BioCyc; BSUB:BSU00320-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR InterPro; IPR007557; PSP1_C.
DR Pfam; PF04468; PSP1; 1.
DR PROSITE; PS51411; PSP1_C; 1.
PE 4: Predicted;
KW Cytoplasm; Reference proteome; Sporulation.
FT CHAIN 1..275
FT /note="Stage 0 sporulation protein YaaT"
FT /id="PRO_0000049437"
FT DOMAIN 61..146
FT /note="PSP1 C-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00744"
SQ SEQUENCE 275 AA; 31219 MW; 0ABC33B7AFC10DDC CRC64;
MYNVIGVRFK KAGKIYYFDP NGFHIEHDSC VIVETVRGVE YGQVVIANKQ VDEHDVVLPL
RKVIRVADDR DLLIVEENKQ EALSAFDICQ KKVIEHGLDM KLVDVEFTFD RNKVIFYFTA
DGRVDFRELV KDLASIFKTR IELRQIGVRD EAKMLGGIGP CGRMLCCSTF LGDFEPVSIK
MAKDQNLSLN PTKISGLCGR LMCCLKYEND EYETAKEQLP DIGEMITTAN GPAKVVGLNI
LERVLQVELI NREKVIEYTW EELLEEGVVS AQTTD