YAAU_ECOLI
ID YAAU_ECOLI Reviewed; 443 AA.
AC P31679; P31578; P75628;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 03-AUG-2022, entry version 161.
DE RecName: Full=Putative metabolite transport protein YaaU;
GN Name=yaaU; Synonyms=yabE; OrderedLocusNames=b0045, JW0044;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=1630901; DOI=10.1093/nar/20.13.3305;
RA Yura T., Mori H., Nagai H., Nagata T., Ishihama A., Fujita N., Isono K.,
RA Mizobuchi K., Nakata A.;
RT "Systematic sequencing of the Escherichia coli genome: analysis of the 0-
RT 2.4 min region.";
RL Nucleic Acids Res. 20:3305-3308(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND SEQUENCE REVISION.
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000305}.
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DR EMBL; U00096; AAC73156.1; -; Genomic_DNA.
DR EMBL; AP009048; BAB96613.2; -; Genomic_DNA.
DR PIR; E64725; E64725.
DR RefSeq; NP_414587.1; NC_000913.3.
DR RefSeq; WP_001183198.1; NZ_STEB01000010.1.
DR AlphaFoldDB; P31679; -.
DR SMR; P31679; -.
DR BioGRID; 4262202; 181.
DR STRING; 511145.b0045; -.
DR TCDB; 2.A.1.1.114; the major facilitator superfamily (mfs).
DR PaxDb; P31679; -.
DR PRIDE; P31679; -.
DR EnsemblBacteria; AAC73156; AAC73156; b0045.
DR EnsemblBacteria; BAB96613; BAB96613; BAB96613.
DR GeneID; 66671665; -.
DR GeneID; 944766; -.
DR KEGG; ecj:JW0044; -.
DR KEGG; eco:b0045; -.
DR PATRIC; fig|1411691.4.peg.2238; -.
DR EchoBASE; EB1527; -.
DR eggNOG; COG2271; Bacteria.
DR HOGENOM; CLU_001265_46_6_6; -.
DR InParanoid; P31679; -.
DR OMA; IAQTCIG; -.
DR PhylomeDB; P31679; -.
DR BioCyc; EcoCyc:YAAU-MON; -.
DR PRO; PR:P31679; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006979; P:response to oxidative stress; IMP:EcoCyc.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF00083; Sugar_tr; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..443
FT /note="Putative metabolite transport protein YaaU"
FT /id="PRO_0000050481"
FT TOPO_DOM 1..18
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 19..39
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 40..53
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 54..74
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 75..84
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 85..105
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 106..113
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 114..134
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 135..145
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 146..166
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 167..173
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 174..194
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 195..241
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 242..262
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 263..282
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 283..303
FT /note="Helical; Name=8"
FT /evidence="ECO:0000255"
FT TOPO_DOM 304..309
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 310..329
FT /note="Helical; Name=9"
FT /evidence="ECO:0000255"
FT TOPO_DOM 330..334
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 335..357
FT /note="Helical; Name=10"
FT /evidence="ECO:0000255"
FT TOPO_DOM 358..373
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 374..394
FT /note="Helical; Name=11"
FT /evidence="ECO:0000255"
FT TOPO_DOM 395..401
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 402..422
FT /note="Helical; Name=12"
FT /evidence="ECO:0000255"
FT TOPO_DOM 423..443
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 443 AA; 48667 MW; AEF484D8B109DE05 CRC64;
MQPSRNFDDL KFSSIHRRIL LWGSGGPFLD GYVLVMIGVA LEQLTPALKL DADWIGLLGA
GTLAGLFVGT SLFGYISDKV GRRKMFLIDI IAIGVISVAT MFVSSPVELL VMRVLIGIVI
GADYPIATSM ITEFSSTRQR AFSISFIAAM WYVGATCADL VGYWLYDVEG GWRWMLGSAA
IPCLLILIGR FELPESPRWL LRKGRVKECE EMMIKLFGEP VAFDEEQPQQ TRFRDLFNRR
HFPFVLFVAA IWTCQVIPMF AIYTFGPQIV GLLGLGVGKN AALGNVVISL FFMLGCIPPM
LWLNTAGRRP LLIGSFAMMT LALAVLGLIP DMGIWLVVMA FAVYAFFSGG PGNLQWLYPN
ELFPTDIRAS AVGVIMSLSR IGTIVSTWAL PIFINNYGIS NTMLMGAGIS LFGLLISVAF
APETRGMSLA QTSNMTIRGQ RMG
