YAB5_ARATH
ID YAB5_ARATH Reviewed; 164 AA.
AC Q8GW46; O48725;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Axial regulator YABBY 5;
GN Name=YAB5; OrderedLocusNames=At2g26580; ORFNames=T9J22.25;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=10679447; DOI=10.1016/s1369-5266(99)00035-7;
RA Bowman J.L.;
RT "The YABBY gene family and abaxial cell fate.";
RL Curr. Opin. Plant Biol. 3:17-22(2000).
RN [6]
RP FUNCTION, DISRUPTION PHENOTYPE, AND INTERACTION WITH LUG AND LUH.
RX PubMed=19837869; DOI=10.1105/tpc.109.070458;
RA Stahle M.I., Kuehlich J., Staron L., von Arnim A.G., Golz J.F.;
RT "YABBYs and the transcriptional corepressors LEUNIG and LEUNIG_HOMOLOG
RT maintain leaf polarity and meristem activity in Arabidopsis.";
RL Plant Cell 21:3105-3118(2009).
RN [7]
RP INTERACTION WITH SPL/NZZ AND SPEAR2.
RX PubMed=25527103; DOI=10.1016/j.jgg.2014.08.009;
RA Chen G.H., Sun J.Y., Liu M., Liu J., Yang W.C.;
RT "SPOROCYTELESS is a novel embryophyte-specific transcription repressor that
RT interacts with TPL and TCP proteins in Arabidopsis.";
RL J. Genet. Genomics 41:617-625(2014).
CC -!- FUNCTION: Promotes adaxial cell identity. Regulates the initiation of
CC embryonic shoot apical meristem (SAM) development.
CC {ECO:0000269|PubMed:19837869}.
CC -!- SUBUNIT: Binds to LUG and LUH; these complexes promote adaxial cell
CC identity in leaves as well as embryonic shoot apical meristem (SAM)
CC initiation and postembryonic SAM maintenance. Interacts with SPL/NZZ
CC and SPEAR2 (PubMed:25527103). {ECO:0000269|PubMed:19837869,
CC ECO:0000269|PubMed:25527103}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- DISRUPTION PHENOTYPE: Leaves polarity and growth defects.
CC {ECO:0000269|PubMed:19837869}.
CC -!- SIMILARITY: Belongs to the YABBY family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC14507.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC002505; AAC14507.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC07860.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07861.1; -; Genomic_DNA.
DR EMBL; AK119091; BAC43665.1; -; mRNA.
DR EMBL; BT003734; AAO39962.1; -; mRNA.
DR PIR; T00991; T00991.
DR RefSeq; NP_850080.1; NM_179749.3.
DR RefSeq; NP_850081.1; NM_179750.3.
DR AlphaFoldDB; Q8GW46; -.
DR SMR; Q8GW46; -.
DR BioGRID; 2551; 8.
DR IntAct; Q8GW46; 8.
DR STRING; 3702.AT2G26580.1; -.
DR PaxDb; Q8GW46; -.
DR PRIDE; Q8GW46; -.
DR EnsemblPlants; AT2G26580.1; AT2G26580.1; AT2G26580.
DR EnsemblPlants; AT2G26580.2; AT2G26580.2; AT2G26580.
DR GeneID; 817199; -.
DR Gramene; AT2G26580.1; AT2G26580.1; AT2G26580.
DR Gramene; AT2G26580.2; AT2G26580.2; AT2G26580.
DR KEGG; ath:AT2G26580; -.
DR Araport; AT2G26580; -.
DR TAIR; locus:2066311; AT2G26580.
DR eggNOG; ENOG502R9GD; Eukaryota.
DR HOGENOM; CLU_071156_0_1_1; -.
DR InParanoid; Q8GW46; -.
DR OMA; NYAVPEY; -.
DR OrthoDB; 1315154at2759; -.
DR PhylomeDB; Q8GW46; -.
DR PRO; PR:Q8GW46; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8GW46; baseline and differential.
DR Genevisible; Q8GW46; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0010158; P:abaxial cell fate specification; IBA:GO_Central.
DR GO; GO:0045165; P:cell fate commitment; IBA:GO_Central.
DR GO; GO:0009944; P:polarity specification of adaxial/abaxial axis; IMP:UniProtKB.
DR GO; GO:2000024; P:regulation of leaf development; IMP:UniProtKB.
DR GO; GO:1902183; P:regulation of shoot apical meristem development; IMP:UniProtKB.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 1.10.30.10; -; 1.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR006780; YABBY.
DR PANTHER; PTHR31675; PTHR31675; 1.
DR Pfam; PF04690; YABBY; 1.
DR SUPFAM; SSF47095; SSF47095; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..164
FT /note="Axial regulator YABBY 5"
FT /id="PRO_0000133721"
FT ZN_FING 16..43
FT /note="C4-type"
FT /evidence="ECO:0000250"
SQ SEQUENCE 164 AA; 18505 MW; 3CDB12D5AA328D31 CRC64;
MANSVMATEQ LCYIPCNFCN IILAVNVPCS SLFDIVTVRC GHCTNLWSVN MAAALQSLSR
PNFQATNYAV PEYGSSSRSH TKIPSRISTR TITEQRIVNR PPEKRQRVPS AYNQFIKEEI
QRIKANNPDI SHREAFSTAA KNWAHFPHIH FGLMLESNKQ AKIA
