YABB_BACSU
ID YABB_BACSU Reviewed; 247 AA.
AC P37543;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Probable RNA methyltransferase YabB {ECO:0000303|PubMed:32324221};
GN Name=yabB; OrderedLocusNames=BSU00340;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=7584024; DOI=10.1093/dnares/1.1.1;
RA Ogasawara N., Nakai S., Yoshikawa H.;
RT "Systematic sequencing of the 180 kilobase region of the Bacillus subtilis
RT chromosome containing the replication origin.";
RL DNA Res. 1:1-14(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RC STRAIN=168 / PY79;
RX PubMed=32324221; DOI=10.1093/nar/gkaa266;
RA Nye T.M., van Gijtenbeek L.A., Stevens A.G., Schroeder J.W., Randall J.R.,
RA Matthews L.A., Simmons L.A.;
RT "Methyltransferase DnmA is responsible for genome-wide N6-methyladenosine
RT modifications at non-palindromic recognition sites in Bacillus subtilis.";
RL Nucleic Acids Res. 48:5332-5348(2020).
CC -!- FUNCTION: Methylates cellular RNA. {ECO:0000269|PubMed:32324221}.
CC -!- DISRUPTION PHENOTYPE: No visible growth defects, DNA is still
CC methylated on A-5 of 5'-GACGAG-3'. {ECO:0000269|PubMed:32324221}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000305}.
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DR EMBL; D26185; BAA05270.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB11810.1; -; Genomic_DNA.
DR PIR; S66064; S66064.
DR RefSeq; NP_387915.1; NC_000964.3.
DR RefSeq; WP_003244526.1; NZ_JNCM01000028.1.
DR AlphaFoldDB; P37543; -.
DR SMR; P37543; -.
DR STRING; 224308.BSU00340; -.
DR PaxDb; P37543; -.
DR PRIDE; P37543; -.
DR EnsemblBacteria; CAB11810; CAB11810; BSU_00340.
DR GeneID; 937011; -.
DR KEGG; bsu:BSU00340; -.
DR PATRIC; fig|224308.179.peg.34; -.
DR eggNOG; COG4123; Bacteria.
DR InParanoid; P37543; -.
DR OMA; GLLCARD; -.
DR PhylomeDB; P37543; -.
DR BioCyc; BSUB:BSU00340-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; -; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR Pfam; PF05175; MTS; 1.
DR SUPFAM; SSF53335; SSF53335; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..247
FT /note="Probable RNA methyltransferase YabB"
FT /id="PRO_0000049438"
SQ SEQUENCE 247 AA; 28282 MW; 88049FCDA9DA894C CRC64;
MVSLHDDERL DYLLAEDMKI IQSPTVFAFS LDAVLLSKFA YVPIQKGKIV DLCTGNGIVP
LLLSTRSKAD ILGVEIQERL HDMAVRSVEY NKLDDQIQII HDDLKNMPEK LGHNRYDVVT
CNPPYFKTPK QTEQNMNEHL RIARHEIHCT LEDVISVSSK LLKQGGKAAL VHRPGRLLEI
FELMKAYQIE PKRVQFVYPK QGKEANTILV EGIKGGRPDL KILPPLFVYD EQNEYTKEIR
TILYGDK