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YABB_BACSU
ID   YABB_BACSU              Reviewed;         247 AA.
AC   P37543;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Probable RNA methyltransferase YabB {ECO:0000303|PubMed:32324221};
GN   Name=yabB; OrderedLocusNames=BSU00340;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=7584024; DOI=10.1093/dnares/1.1.1;
RA   Ogasawara N., Nakai S., Yoshikawa H.;
RT   "Systematic sequencing of the 180 kilobase region of the Bacillus subtilis
RT   chromosome containing the replication origin.";
RL   DNA Res. 1:1-14(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=168 / PY79;
RX   PubMed=32324221; DOI=10.1093/nar/gkaa266;
RA   Nye T.M., van Gijtenbeek L.A., Stevens A.G., Schroeder J.W., Randall J.R.,
RA   Matthews L.A., Simmons L.A.;
RT   "Methyltransferase DnmA is responsible for genome-wide N6-methyladenosine
RT   modifications at non-palindromic recognition sites in Bacillus subtilis.";
RL   Nucleic Acids Res. 48:5332-5348(2020).
CC   -!- FUNCTION: Methylates cellular RNA. {ECO:0000269|PubMed:32324221}.
CC   -!- DISRUPTION PHENOTYPE: No visible growth defects, DNA is still
CC       methylated on A-5 of 5'-GACGAG-3'. {ECO:0000269|PubMed:32324221}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       {ECO:0000305}.
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DR   EMBL; D26185; BAA05270.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB11810.1; -; Genomic_DNA.
DR   PIR; S66064; S66064.
DR   RefSeq; NP_387915.1; NC_000964.3.
DR   RefSeq; WP_003244526.1; NZ_JNCM01000028.1.
DR   AlphaFoldDB; P37543; -.
DR   SMR; P37543; -.
DR   STRING; 224308.BSU00340; -.
DR   PaxDb; P37543; -.
DR   PRIDE; P37543; -.
DR   EnsemblBacteria; CAB11810; CAB11810; BSU_00340.
DR   GeneID; 937011; -.
DR   KEGG; bsu:BSU00340; -.
DR   PATRIC; fig|224308.179.peg.34; -.
DR   eggNOG; COG4123; Bacteria.
DR   InParanoid; P37543; -.
DR   OMA; GLLCARD; -.
DR   PhylomeDB; P37543; -.
DR   BioCyc; BSUB:BSU00340-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR007848; Small_mtfrase_dom.
DR   Pfam; PF05175; MTS; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..247
FT                   /note="Probable RNA methyltransferase YabB"
FT                   /id="PRO_0000049438"
SQ   SEQUENCE   247 AA;  28282 MW;  88049FCDA9DA894C CRC64;
     MVSLHDDERL DYLLAEDMKI IQSPTVFAFS LDAVLLSKFA YVPIQKGKIV DLCTGNGIVP
     LLLSTRSKAD ILGVEIQERL HDMAVRSVEY NKLDDQIQII HDDLKNMPEK LGHNRYDVVT
     CNPPYFKTPK QTEQNMNEHL RIARHEIHCT LEDVISVSSK LLKQGGKAAL VHRPGRLLEI
     FELMKAYQIE PKRVQFVYPK QGKEANTILV EGIKGGRPDL KILPPLFVYD EQNEYTKEIR
     TILYGDK
 
 
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