ID   YABE_BACSU              Reviewed;         407 AA.
AC   P37546;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   17-JUN-2020, sequence version 2.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Putative cell wall shaping protein YabE {ECO:0000305};
DE   Flags: Precursor;
GN   Name=yabE; OrderedLocusNames=BSU00400;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=7584024; DOI=10.1093/dnares/1.1.1;
RA   Ogasawara N., Nakai S., Yoshikawa H.;
RT   "Systematic sequencing of the 180 kilobase region of the Bacillus subtilis
RT   chromosome containing the replication origin.";
RL   DNA Res. 1:1-14(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   DISCUSSION OF POSSIBLE FUNCTION.
RX   PubMed=15774001; DOI=10.1186/1471-2164-6-39;
RA   Ravagnani A., Finan C.L., Young M.;
RT   "A novel firmicute protein family related to the actinobacterial
RT   resuscitation-promoting factors by non-orthologous domain displacement.";
RL   BMC Genomics 6:39-39(2005).
RN   [4]
RP   CORRECTION TO START CODON, INDUCTION, AND DISRUPTION PHENOTYPE.
RX   PubMed=19047346; DOI=10.1128/jb.01530-08;
RA   Eiamphungporn W., Helmann J.D.;
RT   "Extracytoplasmic function sigma factors regulate expression of the
RT   Bacillus subtilis yabE gene via a cis-acting antisense RNA.";
RL   J. Bacteriol. 191:1101-1105(2009).
CC   -!- FUNCTION: Suggested to be involved in cell wall modification.
CC       {ECO:0000303|PubMed:15774001}.
CC   -!- INDUCTION: Negatively regulated by an overlapping cis-acting antisense
CC       RNA which itself is positively regulated by extracytoplasmic sigma
CC       factors SigM and SigX; when both sigma factors are deleted expression
CC       of the yabE mRNA is detected. {ECO:0000269|PubMed:19047346}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype during recovery from
CC       stationary phase or sporulation efficiency.
CC       {ECO:0000269|PubMed:19047346}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA05275.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC       Sequence=CAB11816.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; D26185; BAA05275.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AL009126; CAB11816.1; ALT_INIT; Genomic_DNA.
DR   PIR; S66069; S66069.
DR   RefSeq; NP_387921.1; NC_000964.3.
DR   AlphaFoldDB; P37546; -.
DR   SMR; P37546; -.
DR   STRING; 224308.BSU00400; -.
DR   PaxDb; P37546; -.
DR   PRIDE; P37546; -.
DR   EnsemblBacteria; CAB11816; CAB11816; BSU_00400.
DR   GeneID; 936891; -.
DR   KEGG; bsu:BSU00400; -.
DR   PATRIC; fig|224308.179.peg.40; -.
DR   eggNOG; COG3583; Bacteria.
DR   eggNOG; COG3584; Bacteria.
DR   InParanoid; P37546; -.
DR   PhylomeDB; P37546; -.
DR   BioCyc; BSUB:BSU00400-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0009254; P:peptidoglycan turnover; IEA:InterPro.
DR   Gene3D; 2.40.40.10; -; 1.
DR   InterPro; IPR010611; 3D_dom.
DR   InterPro; IPR007137; DUF348.
DR   InterPro; IPR011098; G5_dom.
DR   InterPro; IPR036908; RlpA-like_sf.
DR   Pfam; PF06725; 3D; 1.
DR   Pfam; PF03990; DUF348; 3.
DR   Pfam; PF07501; G5; 1.
DR   SMART; SM01208; G5; 1.
DR   SUPFAM; SSF50685; SSF50685; 1.
DR   PROSITE; PS51109; G5; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Signal.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000255"
FT   CHAIN           32..407
FT                   /note="Putative cell wall shaping protein YabE"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000049439"
FT   DOMAIN          206..286
FT                   /note="G5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00437"
SQ   SEQUENCE   407 AA;  44209 MW;  4F632877838DB775 CRC64;
     MKKLFSVKLS KSKVILVAAC LLLAGSGTAY AAHELTKQSV SVSINGKKKH IRTHANTVGD
     LLETLDIKTR DEDKITPAKQ TKITADMDVV YEAAKPVKLT INGEEKTLWS TAKTVGALLD
     EQDVDVKEQD QIDPAIDTDI SKDMKINIEP AFQVTVNDAG KQKKIWTTST TVADFLKQQK
     MNIKDEDKIK PALDAKLTKG KADITITRIE KVTDVVEEKI AFDVKKQEDA SLEKGKEKVV
     QKGKEGKLKK HFEVVKENGK EVSRELVKEE TAEQSKDKVI AVGTKQSSPK FETVSASGDS
     KTVVSRSNES TGKVMTVSST AYTASCSGCS GHTATGVNLK NNPNAKVIAV DPNVIPLGSK
     VHVEGYGYAI AADTGSAIKG NKIDVFFPEK SSAYRWGNKT VKIKILN