ID   YACD_BACSU              Reviewed;         297 AA.
AC   P37566;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Putative peptidyl-prolyl cis-trans isomerase YacD;
DE            Short=PPIase YacD;
DE            EC=5.2.1.8;
DE   AltName: Full=Rotamase YacD;
DE   Flags: Precursor;
GN   Name=yacD; OrderedLocusNames=BSU00720;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=7584024; DOI=10.1093/dnares/1.1.1;
RA   Ogasawara N., Nakai S., Yoshikawa H.;
RT   "Systematic sequencing of the 180 kilobase region of the Bacillus subtilis
RT   chromosome containing the replication origin.";
RL   DNA Res. 1:1-14(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[protein]-peptidylproline (omega=180) = [protein]-
CC         peptidylproline (omega=0); Xref=Rhea:RHEA:16237, Rhea:RHEA-
CC         COMP:10747, Rhea:RHEA-COMP:10748, ChEBI:CHEBI:83833,
CC         ChEBI:CHEBI:83834; EC=5.2.1.8;
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DR   EMBL; D26185; BAA05307.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB11848.1; -; Genomic_DNA.
DR   PIR; S66102; S66102.
DR   RefSeq; NP_387953.1; NC_000964.3.
DR   RefSeq; WP_003243824.1; NZ_JNCM01000028.1.
DR   AlphaFoldDB; P37566; -.
DR   SMR; P37566; -.
DR   STRING; 224308.BSU00720; -.
DR   PaxDb; P37566; -.
DR   PRIDE; P37566; -.
DR   DNASU; 936955; -.
DR   EnsemblBacteria; CAB11848; CAB11848; BSU_00720.
DR   GeneID; 936955; -.
DR   KEGG; bsu:BSU00720; -.
DR   PATRIC; fig|224308.179.peg.72; -.
DR   eggNOG; COG0760; Bacteria.
DR   InParanoid; P37566; -.
DR   OMA; WKDQIRY; -.
DR   PhylomeDB; P37566; -.
DR   BioCyc; BSUB:BSU00720-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.50.40; -; 1.
DR   InterPro; IPR046357; PPIase_dom_sf.
DR   InterPro; IPR000297; PPIase_PpiC.
DR   InterPro; IPR023058; PPIase_PpiC_CS.
DR   InterPro; IPR027304; Trigger_fact/SurA_dom_sf.
DR   Pfam; PF13145; Rotamase_2; 1.
DR   SUPFAM; SSF109998; SSF109998; 1.
DR   PROSITE; PS01096; PPIC_PPIASE_1; 1.
DR   PROSITE; PS50198; PPIC_PPIASE_2; 1.
PE   3: Inferred from homology;
KW   Isomerase; Reference proteome; Rotamase; Signal.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000255"
FT   CHAIN           33..297
FT                   /note="Putative peptidyl-prolyl cis-trans isomerase YacD"
FT                   /id="PRO_0000193431"
FT   DOMAIN          154..247
FT                   /note="PpiC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00278"
SQ   SEQUENCE   297 AA;  34096 MW;  551B5DEA5E64657B CRC64;
     MKSRTIWTII LGALLVCCIA VAYTLTKSQA GASSSGESIA TIGGKSVTRE EWLKEMEDQY
     GKSTLEDMIN VRVVEQLAKK NKLKISKSEV DREFLLIKAV NNSFYEDEHT TEKEWKDQIR
     YNILLEDLLT RDIDISNKEL ESFYNKNKEL YQFDDSYRIR HIVVKDEEEA REVLKELKGG
     SSFEAVAAER STDRYTSPYG GDLGFVTEAS DNIPSAYIEE AKTLKEDEWS QEPIKVSNGY
     AIIQLKEKLK ARTFSFDEVK DQIRRQIAMD QLGDKATVKT LWKEADVSWF YGEKSTK