YADG_ECOLI
ID YADG_ECOLI Reviewed; 308 AA.
AC P36879;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 03-AUG-2022, entry version 157.
DE RecName: Full=Uncharacterized ABC transporter ATP-binding protein YadG;
GN Name=yadG; OrderedLocusNames=b0127, JW0123;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8202364; DOI=10.1093/nar/22.9.1637;
RA Fujita N., Mori H., Yura T., Ishihama A.;
RT "Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-
RT 4.1 min (110,917-193,643 bp) region.";
RL Nucleic Acids Res. 22:1637-1639(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP INDUCTION BY 2,4,6-TRINITROTOLUENE, AND BIOTECHNOLOGY.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=25561288; DOI=10.1007/s12013-014-0481-8;
RA Tan J., Kan N., Wang W., Ling J., Qu G., Jin J., Shao Y., Liu G., Chen H.;
RT "Construction of 2,4,6-trinitrotoluene biosensors with novel sensing
RT elements from Escherichia coli K-12 MG1655.";
RL Cell Biochem. Biophys. 72:417-428(2015).
CC -!- INTERACTION:
CC P36879; P69910: gadB; NbExp=2; IntAct=EBI-550911, EBI-549514;
CC -!- INDUCTION: Transcription is increased specifically in response to
CC 2,4,6-trinitrotoluene (TNT) and its indicator compounds 1,3-DNB, 2,4-
CC DNT, and 2,6-DNT. {ECO:0000269|PubMed:25561288}.
CC -!- BIOTECHNOLOGY: Has been used to construct a 2,4,6-trinitrotoluene (TNT)
CC biosensor strain. {ECO:0000269|PubMed:25561288}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; U00096; AAC73238.1; -; Genomic_DNA.
DR EMBL; AP009048; BAB96703.1; -; Genomic_DNA.
DR PIR; S45204; S45204.
DR RefSeq; NP_414669.1; NC_000913.3.
DR RefSeq; WP_000150637.1; NZ_STEB01000010.1.
DR AlphaFoldDB; P36879; -.
DR SMR; P36879; -.
DR BioGRID; 4261962; 15.
DR BioGRID; 849233; 1.
DR DIP; DIP-11185N; -.
DR IntAct; P36879; 20.
DR STRING; 511145.b0127; -.
DR TCDB; 3.A.1.105.17; the atp-binding cassette (abc) superfamily.
DR jPOST; P36879; -.
DR PaxDb; P36879; -.
DR PRIDE; P36879; -.
DR EnsemblBacteria; AAC73238; AAC73238; b0127.
DR EnsemblBacteria; BAB96703; BAB96703; BAB96703.
DR GeneID; 66671584; -.
DR GeneID; 944833; -.
DR KEGG; ecj:JW0123; -.
DR KEGG; eco:b0127; -.
DR PATRIC; fig|1411691.4.peg.2155; -.
DR EchoBASE; EB2225; -.
DR eggNOG; COG1131; Bacteria.
DR HOGENOM; CLU_000604_1_2_6; -.
DR InParanoid; P36879; -.
DR OMA; CEGYRRP; -.
DR PhylomeDB; P36879; -.
DR BioCyc; EcoCyc:YADG-MON; -.
DR PRO; PR:P36879; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0010165; P:response to X-ray; IMP:EcoCyc.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Nucleotide-binding; Reference proteome; Transport.
FT CHAIN 1..308
FT /note="Uncharacterized ABC transporter ATP-binding protein
FT YadG"
FT /id="PRO_0000093151"
FT DOMAIN 5..236
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 38..45
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 308 AA; 34647 MW; 9EF43C2BFBFF3F47 CRC64;
MTIALELQQL KKTYPGGVQA LRGIDLQVEA GDFYALLGPN GAGKSTTIGI ISSLVNKTSG
RVSVFGYDLE KDVVNAKRQL GLVPQEFNFN PFETVQQIVV NQAGYYGVER KEAYIRSEKY
LKQLDLWGKR NERARMLSGG MKRRLMIARA LMHEPKLLIL DEPTAGVDIE LRRSMWGFLK
DLNDKGTTII LTTHYLEEAE MLCRNIGIIQ HGELVENTSM KALLAKLKSE TFILDLAPKS
PLPKLDGYQY RLVDTATLEV EVLREQGINS VFTQLSEQGI QVLSMRNKAN RLEELFVSLV
NEKQGDRA
