ID   YADH_ECOL6              Reviewed;         256 AA.
AC   P0AFN7; P36880; P75657; Q8KMY9;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Inner membrane transport permease YadH;
GN   Name=yadH; OrderedLocusNames=c0157;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC-2 integral membrane protein family.
CC       {ECO:0000305}.
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DR   EMBL; AE014075; AAN78651.1; -; Genomic_DNA.
DR   RefSeq; WP_000972203.1; NC_004431.1.
DR   AlphaFoldDB; P0AFN7; -.
DR   SMR; P0AFN7; -.
DR   STRING; 199310.c0157; -.
DR   EnsemblBacteria; AAN78651; AAN78651; c0157.
DR   GeneID; 66671583; -.
DR   KEGG; ecc:c0157; -.
DR   eggNOG; COG0842; Bacteria.
DR   HOGENOM; CLU_039483_3_0_6; -.
DR   OMA; HSLPPFW; -.
DR   BioCyc; ECOL199310:C0157-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR013525; ABC_2_trans.
DR   InterPro; IPR000412; ABC_2_transport.
DR   Pfam; PF01061; ABC2_membrane; 1.
DR   PIRSF; PIRSF006648; DrrB; 1.
DR   PRINTS; PR00164; ABC2TRNSPORT.
DR   PROSITE; PS51012; ABC_TM2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..256
FT                   /note="Inner membrane transport permease YadH"
FT                   /id="PRO_0000183000"
FT   TOPO_DOM        1..22
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        44..52
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        74..94
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        116
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        138
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        139..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        160..169
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        170..190
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        191..223
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        245..256
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          22..251
FT                   /note="ABC transmembrane type-2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00442"
SQ   SEQUENCE   256 AA;  28516 MW;  2AE10E6CB143F708 CRC64;
     MMHLYWVALK SIWAKEIHRF MRIWVQTLVP PVITMTLYFI IFGNLIGSRI GDMHGFSYMQ
     FIVPGLIMMS VITNAYANVA SSFFGAKFQR NIEELLVAPV PTHVIIAGYV GGGVARGLFV
     GILVTAISLF FVPFQVHSWV FVALTLVLTA VLFSLAGLLN GVFAKTFDDI SLVPTFVLTP
     LTYLGGVFYS LTLLPPFWQG LSHLNPIVYM ISGFRYGFLG INDVPLVTTF GVLVVFIVAF
     YLICWSLIQR GRGLRS