YADK_ECOLI
ID YADK_ECOLI Reviewed; 198 AA.
AC P37016;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Uncharacterized fimbrial-like protein YadK;
DE Flags: Precursor;
GN Name=yadK; OrderedLocusNames=b0136, JW0132;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8202364; DOI=10.1093/nar/22.9.1637;
RA Fujita N., Mori H., Yura T., Ishihama A.;
RT "Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-
RT 4.1 min (110,917-193,643 bp) region.";
RL Nucleic Acids Res. 22:1637-1639(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP FUNCTION, INDUCTION, AND DISRUPTION PHENOTYPE.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=20345943; DOI=10.1111/j.1462-2920.2010.02202.x;
RA Korea C.G., Badouraly R., Prevost M.C., Ghigo J.M., Beloin C.;
RT "Escherichia coli K-12 possesses multiple cryptic but functional chaperone-
RT usher fimbriae with distinct surface specificities.";
RL Environ. Microbiol. 12:1957-1977(2010).
CC -!- FUNCTION: Part of the yadCKLM-htrE-yadVN fimbrial operon. Could
CC contribute to adhesion to various surfaces in specific environmental
CC niches. {ECO:0000269|PubMed:20345943}.
CC -!- SUBCELLULAR LOCATION: Fimbrium {ECO:0000305}.
CC -!- INDUCTION: Repressed by H-NS. {ECO:0000269|PubMed:20345943}.
CC -!- DISRUPTION PHENOTYPE: Deletion of the operon under classical laboratory
CC conditions does not result in any major effect on E.coli capacity to
CC form biofilms compared with the wild-type strain.
CC {ECO:0000269|PubMed:20345943}.
CC -!- MISCELLANEOUS: The operon is cryptic under classical laboratory
CC conditions, but is functional when constitutively expressed.
CC {ECO:0000305|PubMed:20345943}.
CC -!- SIMILARITY: Belongs to the fimbrial protein family. {ECO:0000305}.
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DR EMBL; U00096; AAC73247.1; -; Genomic_DNA.
DR EMBL; AP009048; BAB96713.1; -; Genomic_DNA.
DR PIR; H64736; H64736.
DR RefSeq; NP_414678.1; NC_000913.3.
DR RefSeq; WP_000553749.1; NZ_STEB01000010.1.
DR AlphaFoldDB; P37016; -.
DR SMR; P37016; -.
DR BioGRID; 4259739; 12.
DR STRING; 511145.b0136; -.
DR SWISS-2DPAGE; P37016; -.
DR PaxDb; P37016; -.
DR PRIDE; P37016; -.
DR EnsemblBacteria; AAC73247; AAC73247; b0136.
DR EnsemblBacteria; BAB96713; BAB96713; BAB96713.
DR GeneID; 944835; -.
DR KEGG; ecj:JW0132; -.
DR KEGG; eco:b0136; -.
DR PATRIC; fig|1411691.4.peg.2145; -.
DR EchoBASE; EB2229; -.
DR eggNOG; COG3539; Bacteria.
DR HOGENOM; CLU_119930_0_0_6; -.
DR OMA; RYQNTGA; -.
DR BioCyc; EcoCyc:EG12325-MON; -.
DR PRO; PR:P37016; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0009289; C:pilus; IMP:EcoCyc.
DR GO; GO:0007155; P:cell adhesion; IMP:EcoCyc.
DR GO; GO:0043709; P:cell adhesion involved in single-species biofilm formation; IMP:EcoCyc.
DR Gene3D; 2.60.40.1090; -; 1.
DR InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR InterPro; IPR008966; Adhesion_dom_sf.
DR SUPFAM; SSF49401; SSF49401; 1.
PE 2: Evidence at transcript level;
KW Fimbrium; Reference proteome; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..198
FT /note="Uncharacterized fimbrial-like protein YadK"
FT /id="PRO_0000168527"
SQ SEQUENCE 198 AA; 21112 MW; 50DDE81ACF3BD846 CRC64;
MHPTQRKLMK RIILFLSLLF CIACPAIAGQ DIDLVANVKN STCKSGISNQ GNIDLGVVGV
GYFSGNVTPE SYQPGGKEFT ITVSDCALQG TGDVLNQLHI DFRALSGVMA AGSRQIFANE
ISSGASNVGV VIFSTQDSAN TFNVLNASGG SRSVYPVMSD DMNGSSWKFS TRMQKIDPAL
SVTSGQLMSH VLVDIYYE
