YAE1_ASPTN
ID YAE1_ASPTN Reviewed; 220 AA.
AC Q0CX45;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 44.
DE RecName: Full=Protein yae1;
GN Name=yae1; ORFNames=ATEG_01739;
OS Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=341663;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIH 2624 / FGSC A1156;
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA Nierman W.C., Milne T., Madden K.;
RT "Annotation of the Aspergillus terreus NIH2624 genome.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: The complex LTO1:YAE1 may function as a target specific
CC adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur
CC protein assembly (CIA) complex machinery. May be required for
CC biogenesis of the large ribosomal subunit and initiation of
CC translation. {ECO:0000250|UniProtKB:Q9NRH1}.
CC -!- SUBUNIT: May form a complex with LTO1. {ECO:0000250|UniProtKB:Q9NRH1}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P47118}. Nucleus
CC {ECO:0000250|UniProtKB:P47118}.
CC -!- SIMILARITY: Belongs to the YAE1 family. {ECO:0000305}.
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DR EMBL; CH476595; EAU38496.1; -; Genomic_DNA.
DR RefSeq; XP_001209104.1; XM_001209104.1.
DR AlphaFoldDB; Q0CX45; -.
DR STRING; 341663.Q0CX45; -.
DR EnsemblFungi; EAU38496; EAU38496; ATEG_01739.
DR GeneID; 4316370; -.
DR VEuPathDB; FungiDB:ATEG_01739; -.
DR eggNOG; KOG4774; Eukaryota.
DR HOGENOM; CLU_066684_1_1_1; -.
DR OMA; GYRDGTS; -.
DR OrthoDB; 1192442at2759; -.
DR Proteomes; UP000007963; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0106035; P:protein maturation by [4Fe-4S] cluster transfer; ISS:UniProtKB.
DR InterPro; IPR019191; Essential_protein_Yae1_N.
DR InterPro; IPR038881; Yae1-like.
DR PANTHER; PTHR18829; PTHR18829; 1.
DR Pfam; PF09811; Yae1_N; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..220
FT /note="Protein yae1"
FT /id="PRO_0000324421"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 49..89
FT /note="deca-GX3 motif; required for interaction with LTO1"
FT /evidence="ECO:0000250|UniProtKB:P47118"
FT REGION 102..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..34
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 220 AA; 22958 MW; 84B27428A6638B4F CRC64;
MDNSLDDIFG SSPPHETAHP IAPPSNPSPS NPAEPSELPS LRRQHVTAGY RDGISASKGE
HVQAGFDAGF PVGAQLGMRA GTVLGILEGV LRGYESRTSS VVKKPARTAA GGATKSENPN
EADAEARNAK RAEILTLYQQ ALKDLDVQAV FAGLQGAEGE KPETQLGRKG DVAVSGWEKR
VLVAHWEENM EALEAKDDGE GEGAAEEGEA SKAAPAPALS
