ID   YAE1_CANGA              Reviewed;         144 AA.
AC   Q6FUV0;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Protein YAE1;
GN   Name=YAE1; OrderedLocusNames=CAGL0F00473g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: The complex LTO1:YAE1 may function as a target specific
CC       adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur
CC       protein assembly (CIA) complex machinery. May be required for
CC       biogenesis of the large ribosomal subunit and initiation of
CC       translation. {ECO:0000250|UniProtKB:Q9NRH1}.
CC   -!- SUBUNIT: May form a complex with LTO1. {ECO:0000250|UniProtKB:Q9NRH1}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P47118}. Nucleus
CC       {ECO:0000250|UniProtKB:P47118}.
CC   -!- SIMILARITY: Belongs to the YAE1 family. {ECO:0000305}.
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DR   EMBL; CR380952; CAG58918.1; -; Genomic_DNA.
DR   RefSeq; XP_445994.1; XM_445994.1.
DR   AlphaFoldDB; Q6FUV0; -.
DR   SMR; Q6FUV0; -.
DR   STRING; 5478.XP_445994.1; -.
DR   EnsemblFungi; CAG58918; CAG58918; CAGL0F00473g.
DR   GeneID; 2887898; -.
DR   KEGG; cgr:CAGL0F00473g; -.
DR   CGD; CAL0131200; CAGL0F00473g.
DR   VEuPathDB; FungiDB:CAGL0F00473g; -.
DR   eggNOG; KOG4774; Eukaryota.
DR   HOGENOM; CLU_066684_2_0_1; -.
DR   InParanoid; Q6FUV0; -.
DR   OMA; DESYHEL; -.
DR   Proteomes; UP000002428; Chromosome F.
DR   GO; GO:0097361; C:CIA complex; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0062092; C:Yae1-Lto1 complex; IEA:EnsemblFungi.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:EnsemblFungi.
DR   GO; GO:0106035; P:protein maturation by [4Fe-4S] cluster transfer; ISS:UniProtKB.
DR   InterPro; IPR019191; Essential_protein_Yae1_N.
DR   InterPro; IPR038881; Yae1-like.
DR   PANTHER; PTHR18829; PTHR18829; 1.
DR   Pfam; PF09811; Yae1_N; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..144
FT                   /note="Protein YAE1"
FT                   /id="PRO_0000324424"
FT   REGION          37..77
FT                   /note="deca-GX3 motif; required for interaction with LTO1"
FT                   /evidence="ECO:0000250|UniProtKB:P47118"
SQ   SEQUENCE   144 AA;  16604 MW;  C917EE72DDB4A1DB CRC64;
     MADLLDDVWG SGDDLDESTR ELSPDLLKLK DNHSKRGYLD GIVSAKEENL QDGFDMSFPL
     GAELGLRVGK IIGRLQGLEY RYGKDDEELK KDFNNAKQEL QIKNILTKRI FTEDYNLEDS
     KHPVVSKWEE IVTKYCEKYN VKTE