ID   YAE1_SCLS1              Reviewed;         243 AA.
AC   A7EB95;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Protein yae1;
GN   Name=yae1; ORFNames=SS1G_02581;
OS   Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS   (Whetzelinia sclerotiorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Sclerotinia.
OX   NCBI_TaxID=665079;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18683 / 1980 / Ss-1;
RX   PubMed=21876677; DOI=10.1371/journal.pgen.1002230;
RA   Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A.,
RA   Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA   Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M.,
RA   Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA   Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA   Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA   Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA   Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C.,
RA   Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA   Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA   Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA   Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA   Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.;
RT   "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT   sclerotiorum and Botrytis cinerea.";
RL   PLoS Genet. 7:E1002230-E1002230(2011).
CC   -!- FUNCTION: The complex LTO1:YAE1 may function as a target specific
CC       adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur
CC       protein assembly (CIA) complex machinery. May be required for
CC       biogenesis of the large ribosomal subunit and initiation of
CC       translation. {ECO:0000250|UniProtKB:Q9NRH1}.
CC   -!- SUBUNIT: May form a complex with LTO1. {ECO:0000250|UniProtKB:Q9NRH1}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P47118}. Nucleus
CC       {ECO:0000250|UniProtKB:P47118}.
CC   -!- SIMILARITY: Belongs to the YAE1 family. {ECO:0000305}.
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DR   EMBL; CH476623; EDN99723.1; -; Genomic_DNA.
DR   RefSeq; XP_001596361.1; XM_001596311.1.
DR   AlphaFoldDB; A7EB95; -.
DR   STRING; 665079.A7EB95; -.
DR   EnsemblFungi; EDN99723; EDN99723; SS1G_02581.
DR   GeneID; 5492121; -.
DR   KEGG; ssl:SS1G_02581; -.
DR   VEuPathDB; FungiDB:sscle_04g035630; -.
DR   eggNOG; KOG4774; Eukaryota.
DR   HOGENOM; CLU_066684_0_1_1; -.
DR   InParanoid; A7EB95; -.
DR   OMA; MHFQPVE; -.
DR   Proteomes; UP000001312; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0106035; P:protein maturation by [4Fe-4S] cluster transfer; ISS:UniProtKB.
DR   InterPro; IPR019191; Essential_protein_Yae1_N.
DR   InterPro; IPR038881; Yae1-like.
DR   PANTHER; PTHR18829; PTHR18829; 1.
DR   Pfam; PF09811; Yae1_N; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..243
FT                   /note="Protein yae1"
FT                   /id="PRO_0000324434"
FT   REGION          36..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          73..113
FT                   /note="deca-GX3 motif; required for interaction with LTO1"
FT                   /evidence="ECO:0000250|UniProtKB:P47118"
SQ   SEQUENCE   243 AA;  26961 MW;  7000C5B850D3A90D CRC64;
     MFRDHEFPLS SGAFSILTSE SAVLNDDFDD VFGSEPGSPA FDVRDGHDGD TFGGGNTEIS
     DIPRLKEKHE TEGYRDGVTK GKAESVQKGF DEGYGLGAVL GLRIGKVIGI LEGIFGAVSV
     SAAKSEDTKW TDERSRLEEL FKSAKEELKT EKVFAREWWG EDGIWKFEVP GEKEGKDVVF
     PDVAAAHPLL KKWEGLVEEE IQRWSLDLEF MEGNEEEAVP AKQQIKADAV EQKMGTVKTD
     LNW