ID   YAE1_YARLI              Reviewed;         121 AA.
AC   Q6C531;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Protein YAE1;
GN   Name=YAE1; OrderedLocusNames=YALI0E21505g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: The complex LTO1:YAE1 may function as a target specific
CC       adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur
CC       protein assembly (CIA) complex machinery. May be required for
CC       biogenesis of the large ribosomal subunit and initiation of
CC       translation. {ECO:0000250|UniProtKB:Q9NRH1}.
CC   -!- SUBUNIT: May form a complex with LTO1. {ECO:0000250|UniProtKB:Q9NRH1}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P47118}. Nucleus
CC       {ECO:0000250|UniProtKB:P47118}.
CC   -!- SIMILARITY: Belongs to the YAE1 family. {ECO:0000305}.
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DR   EMBL; CR382131; CAG79826.1; -; Genomic_DNA.
DR   RefSeq; XP_504231.1; XM_504231.1.
DR   AlphaFoldDB; Q6C531; -.
DR   STRING; 4952.CAG79826; -.
DR   EnsemblFungi; CAG79826; CAG79826; YALI0_E21505g.
DR   GeneID; 2911898; -.
DR   KEGG; yli:YALI0E21505g; -.
DR   VEuPathDB; FungiDB:YALI0_E21505g; -.
DR   HOGENOM; CLU_066684_2_0_1; -.
DR   InParanoid; Q6C531; -.
DR   OMA; REGINDD; -.
DR   Proteomes; UP000001300; Chromosome E.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0106035; P:protein maturation by [4Fe-4S] cluster transfer; ISS:UniProtKB.
DR   InterPro; IPR019191; Essential_protein_Yae1_N.
DR   Pfam; PF09811; Yae1_N; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..121
FT                   /note="Protein YAE1"
FT                   /id="PRO_0000324436"
FT   REGION          28..68
FT                   /note="deca-GX3 motif; required for interaction with LTO1"
FT                   /evidence="ECO:0000250|UniProtKB:P47118"
SQ   SEQUENCE   121 AA;  13777 MW;  734242500C1B8EE3 CRC64;
     MSDIWDDEEV RETPSEITRV KRDHSQAGYL AGVTKAKDES LQEGFNAGYP IGGQLGLSIG
     RIFGYLQGKG LVEEEKQARK ELSSTRIFDR QYWTTDAAPT YEGVHPLVKQ WENKIDVMKR
     E