ID   YAFD_SHIFL              Reviewed;         266 AA.
AC   P0A8U5; P30865; P75671;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=UPF0294 protein YafD;
GN   Name=yafD; OrderedLocusNames=SF0195, S0203;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0294 family. {ECO:0000305}.
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DR   EMBL; AE005674; AAN41857.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP15737.1; -; Genomic_DNA.
DR   RefSeq; NP_706150.1; NC_004337.2.
DR   RefSeq; WP_001230983.1; NZ_WPGN01000098.1.
DR   AlphaFoldDB; P0A8U5; -.
DR   SMR; P0A8U5; -.
DR   STRING; 198214.SF0195; -.
DR   EnsemblBacteria; AAN41857; AAN41857; SF0195.
DR   EnsemblBacteria; AAP15737; AAP15737; S0203.
DR   GeneID; 1024437; -.
DR   GeneID; 66671501; -.
DR   KEGG; sfl:SF0195; -.
DR   KEGG; sfx:S0203; -.
DR   PATRIC; fig|198214.7.peg.218; -.
DR   HOGENOM; CLU_083563_0_0_6; -.
DR   OMA; HAINFSF; -.
DR   OrthoDB; 1387978at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 3.60.10.10; -; 1.
DR   HAMAP; MF_01119; UPF0294; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR022958; UPF0294.
DR   Pfam; PF03372; Exo_endo_phos; 1.
DR   SUPFAM; SSF56219; SSF56219; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..266
FT                   /note="UPF0294 protein YafD"
FT                   /id="PRO_0000074643"
SQ   SEQUENCE   266 AA;  29992 MW;  5F5AD2B0C4CE5794 CRC64;
     MRKNTYAMRY VAGQPAERIL PPGSFASIGQ ALPPGEPLST EERIRILVWN IYKQQRAEWL
     SVLKNYGKDA HLVLLQEAQT TPELVQFATA NYLAADQVPA FVLPQHPSGV MTLSAAHPVY
     CCPLREREPI LRLAKSALVT VYPLPDTRLL MVVNIHAVNF SLGVDVYSKQ LLPIGDQIAH
     HSGPVIMAGD FNAWSRRRMN ALYRFAREMS LRQVRFTDDQ RRRAFGRPLD FVFYRGLNVS
     EASVLVTRAS DHNPLLVEFS PGKPDK