CATC2_ACILW
ID CATC2_ACILW Reviewed; 96 AA.
AC O33951;
DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 60.
DE RecName: Full=Muconolactone Delta-isomerase 2;
DE Short=MIase 2;
DE EC=5.3.3.4 {ECO:0000250|UniProtKB:P00948};
GN Name=catC2;
OS Acinetobacter lwoffii.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=28090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K24;
RX PubMed=9260969; DOI=10.1128/jb.179.16.5226-5231.1997;
RA Kim S.I., Leem S.-H., Choi J.-S., Chung Y.H., Kim S., Park Y.-M.,
RA Park Y.K., Lee Y.N., Ha K.-S.;
RT "Cloning and characterization of two catA genes in Acinetobacter lwoffii
RT K24.";
RL J. Bacteriol. 179:5226-5231(1997).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-muconolactone = (4,5-dihydro-5-oxofuran-2-yl)-acetate;
CC Xref=Rhea:RHEA:12348, ChEBI:CHEBI:58425, ChEBI:CHEBI:58736;
CC EC=5.3.3.4; Evidence={ECO:0000250|UniProtKB:P00948};
CC -!- PATHWAY: Aromatic compound metabolism; beta-ketoadipate pathway; 5-oxo-
CC 4,5-dihydro-2-furylacetate from catechol: step 3/3.
CC -!- SUBUNIT: Homodecamer. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the muconolactone Delta-isomerase family.
CC {ECO:0000305}.
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DR EMBL; U77659; AAC31768.1; -; Genomic_DNA.
DR PIR; T46826; T46826.
DR AlphaFoldDB; O33951; -.
DR SMR; O33951; -.
DR UniPathway; UPA00157; UER00260.
DR GO; GO:0016159; F:muconolactone delta-isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0042952; P:beta-ketoadipate pathway; IEA:UniProtKB-UniPathway.
DR InterPro; IPR011008; Dimeric_a/b-barrel.
DR InterPro; IPR026029; MLI_dom.
DR InterPro; IPR003464; Muconolactone_d_Isoase.
DR Pfam; PF02426; MIase; 1.
DR PIRSF; PIRSF001486; CatC; 1.
DR SUPFAM; SSF54909; SSF54909; 1.
DR TIGRFAMs; TIGR03221; muco_delta; 1.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism; Isomerase.
FT CHAIN 1..96
FT /note="Muconolactone Delta-isomerase 2"
FT /id="PRO_0000089332"
SQ SEQUENCE 96 AA; 11130 MW; EC919F35C97A098A CRC64;
MLFHVEMTVN LPSDMDAERA ARLKSDEKAM SQKLQQEGVW RHLWRIAGRY ANISVFDVES
PAHLHDVLSQ LPLFPYMDVE VRALCRHASS IHDDDR