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CATC2_ACILW
ID   CATC2_ACILW             Reviewed;          96 AA.
AC   O33951;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Muconolactone Delta-isomerase 2;
DE            Short=MIase 2;
DE            EC=5.3.3.4 {ECO:0000250|UniProtKB:P00948};
GN   Name=catC2;
OS   Acinetobacter lwoffii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter.
OX   NCBI_TaxID=28090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K24;
RX   PubMed=9260969; DOI=10.1128/jb.179.16.5226-5231.1997;
RA   Kim S.I., Leem S.-H., Choi J.-S., Chung Y.H., Kim S., Park Y.-M.,
RA   Park Y.K., Lee Y.N., Ha K.-S.;
RT   "Cloning and characterization of two catA genes in Acinetobacter lwoffii
RT   K24.";
RL   J. Bacteriol. 179:5226-5231(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-muconolactone = (4,5-dihydro-5-oxofuran-2-yl)-acetate;
CC         Xref=Rhea:RHEA:12348, ChEBI:CHEBI:58425, ChEBI:CHEBI:58736;
CC         EC=5.3.3.4; Evidence={ECO:0000250|UniProtKB:P00948};
CC   -!- PATHWAY: Aromatic compound metabolism; beta-ketoadipate pathway; 5-oxo-
CC       4,5-dihydro-2-furylacetate from catechol: step 3/3.
CC   -!- SUBUNIT: Homodecamer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the muconolactone Delta-isomerase family.
CC       {ECO:0000305}.
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DR   EMBL; U77659; AAC31768.1; -; Genomic_DNA.
DR   PIR; T46826; T46826.
DR   AlphaFoldDB; O33951; -.
DR   SMR; O33951; -.
DR   UniPathway; UPA00157; UER00260.
DR   GO; GO:0016159; F:muconolactone delta-isomerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042952; P:beta-ketoadipate pathway; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR026029; MLI_dom.
DR   InterPro; IPR003464; Muconolactone_d_Isoase.
DR   Pfam; PF02426; MIase; 1.
DR   PIRSF; PIRSF001486; CatC; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   TIGRFAMs; TIGR03221; muco_delta; 1.
PE   3: Inferred from homology;
KW   Aromatic hydrocarbons catabolism; Isomerase.
FT   CHAIN           1..96
FT                   /note="Muconolactone Delta-isomerase 2"
FT                   /id="PRO_0000089332"
SQ   SEQUENCE   96 AA;  11130 MW;  EC919F35C97A098A CRC64;
     MLFHVEMTVN LPSDMDAERA ARLKSDEKAM SQKLQQEGVW RHLWRIAGRY ANISVFDVES
     PAHLHDVLSQ LPLFPYMDVE VRALCRHASS IHDDDR
 
 
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