ID   YAG1_SCHPO              Reviewed;         905 AA.
AC   Q09866; Q9UUH9;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   27-MAR-2002, sequence version 2.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Uncharacterized WD repeat-containing protein C12G12.01c;
GN   ORFNames=SPAC12G12.01c, SPAC630.02;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-394 AND SER-397, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- SIMILARITY: Belongs to the WD repeat mio family. {ECO:0000305}.
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DR   EMBL; CU329670; CAA91496.1; -; Genomic_DNA.
DR   PIR; T38980; T38980.
DR   RefSeq; XP_001713039.1; XM_001712987.2.
DR   AlphaFoldDB; Q09866; -.
DR   SMR; Q09866; -.
DR   BioGRID; 280457; 32.
DR   STRING; 4896.SPAC12G12.01c.1; -.
DR   iPTMnet; Q09866; -.
DR   MaxQB; Q09866; -.
DR   PaxDb; Q09866; -.
DR   PRIDE; Q09866; -.
DR   EnsemblFungi; SPAC12G12.01c.1; SPAC12G12.01c.1:pep; SPAC12G12.01c.
DR   PomBase; SPAC12G12.01c; -.
DR   VEuPathDB; FungiDB:SPAC12G12.01c; -.
DR   eggNOG; KOG1008; Eukaryota.
DR   HOGENOM; CLU_005843_0_0_1; -.
DR   InParanoid; Q09866; -.
DR   OMA; QSHNSTC; -.
DR   PhylomeDB; Q09866; -.
DR   PRO; PR:Q09866; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0061700; C:GATOR2 complex; IPI:PomBase.
DR   GO; GO:0005774; C:vacuolar membrane; EXP:PomBase.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; ISM:PomBase.
DR   GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR   GO; GO:1904263; P:positive regulation of TORC1 signaling; ISO:PomBase.
DR   GO; GO:0070647; P:protein modification by small protein conjugation or removal; IC:PomBase.
DR   CDD; cd16691; mRING-H2-C3H3C2_Mio; 1.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR037593; MIOS/Sea4.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR031488; Zn_ribbon_mio.
DR   PANTHER; PTHR16453; PTHR16453; 1.
DR   Pfam; PF17034; zinc_ribbon_16; 1.
DR   SMART; SM00320; WD40; 3.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..905
FT                   /note="Uncharacterized WD repeat-containing protein
FT                   C12G12.01c"
FT                   /id="PRO_0000051489"
FT   REPEAT          42..82
FT                   /note="WD 1"
FT   REPEAT          86..128
FT                   /note="WD 2"
FT   REPEAT          136..175
FT                   /note="WD 3"
FT   REPEAT          177..217
FT                   /note="WD 4"
FT   MOD_RES         394
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         397
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   905 AA;  101948 MW;  56BCF35CA07F709B CRC64;
     MLNRSKKRNG CYFWVNGSSD EIRYVAVKAS PKVNWKTHII WRSLKNVKCI DSFHGNNEIL
     GAGSSTGNIS LLSVKHPEFQ AVVTPGYARP CNSLAFSETE HLVAGFAKSR NESSLKLWDL
     NSLLSDPKSS PLMQSSTLDG VSSVCYKKDT PLLLTGSTSR SVHIIDTRQQ LDSVSSVNTQ
     YYSNIVVDPF SPNYFAANSY DGDIAIFDTR YFKSDNYLQI ILRNENKKPK NPQLFALKYS
     EWKPGQLAVL SNNSITLRQL LPCVNGNEGS ANNSVFVNYE KKYPVKPNSQ CSGIDFFTPS
     TAFPTHVQIL GVINEQPKLF SVHDEVIPFS FNPYNDLIFS FKEKLYPLNS SPFNTLSDVP
     QFDVSEFVDE NSFDSSSSCS SKVFLTTRNN SINSEDSAHE VLLSYNRVLG SDIQGTILDR
     VKKGYQFDSQ KNSELVSDLY LKDLWSWIHL SHRQSEESLF GDTGDTDFSY QGALGIWFMD
     TELTSMSDVF EAKESKFLEK KILRLARDVI ERLDLDIFTS IQTKRPLRQL ALLACGLGMS
     NDDLLLEIRR LIRKNEHVKA AGLALFHGKI ENVVRILSSG NELEKTISTA VAGYITSQGL
     SNFGSDSLWK EMSRNLSTEL EDPYLRAIFA YVSNSDWRDV LDEVSLSLKD RLGIALRFLP
     DDDLSNYLCD LCHTTVQSGD PEGLLLTGLT PLGMELLQNY IDHTSDVQTA ALIAAFVVPK
     KFLDKRAEDW TESYRELLNR WKLYRERAKF DIFRTELSKN HTGEITRKAT EPSIRIICNF
     CRKPIFPFSN RNECNNLPTP IQRGVSKAGP AKHLGKSCPH CGQPLPKCSV CGFSLGDEDV
     PQKDDFSQKP QNYVKEVNLQ KSRFGLWFSF CLNCGHGAHA SHASEWFSTH TICPVPNCDC
     ECKLK