YAGG_ECOLI
ID YAGG_ECOLI Reviewed; 460 AA.
AC P75683; P71292; Q2MCF2;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 151.
DE RecName: Full=Putative glycoside/cation symporter YagG;
GN Name=yagG; OrderedLocusNames=b0270, JW0263;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RA Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT "Sequence of minutes 4-25 of Escherichia coli.";
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP SUBCELLULAR LOCATION, AND TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein
CC {ECO:0000305|PubMed:15919996}.
CC -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC family. {ECO:0000305}.
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DR EMBL; U70214; AAB08691.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73373.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76054.1; -; Genomic_DNA.
DR PIR; F64752; F64752.
DR RefSeq; NP_414804.1; NC_000913.3.
DR RefSeq; WP_000192863.1; NZ_LN832404.1.
DR AlphaFoldDB; P75683; -.
DR SMR; P75683; -.
DR BioGRID; 4261987; 193.
DR DIP; DIP-11234N; -.
DR IntAct; P75683; 2.
DR STRING; 511145.b0270; -.
DR TCDB; 2.A.2.3.5; the glycoside-pentoside-hexuronide (gph):cation symporter family.
DR PaxDb; P75683; -.
DR PRIDE; P75683; -.
DR EnsemblBacteria; AAC73373; AAC73373; b0270.
DR EnsemblBacteria; BAE76054; BAE76054; BAE76054.
DR GeneID; 944947; -.
DR KEGG; ecj:JW0263; -.
DR KEGG; eco:b0270; -.
DR PATRIC; fig|1411691.4.peg.2010; -.
DR EchoBASE; EB3130; -.
DR eggNOG; COG2211; Bacteria.
DR HOGENOM; CLU_027408_0_2_6; -.
DR InParanoid; P75683; -.
DR OMA; YASFCLG; -.
DR PhylomeDB; P75683; -.
DR BioCyc; EcoCyc:B0270-MON; -.
DR PRO; PR:P75683; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IBA:GO_Central.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 2.
DR InterPro; IPR039672; MFS_2.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR001927; Na/Gal_symport.
DR InterPro; IPR018043; Na/Gal_symport_CS.
DR PANTHER; PTHR11328; PTHR11328; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR TIGRFAMs; TIGR00792; gph; 1.
DR PROSITE; PS00872; NA_GALACTOSIDE_SYMP; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome; Symport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..460
FT /note="Putative glycoside/cation symporter YagG"
FT /id="PRO_0000170765"
FT TOPO_DOM 1..9
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 52..78
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 100..106
FT /note="Periplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 128..150
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 172..179
FT /note="Periplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 201..262
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 263..283
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 284..308
FT /note="Periplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 309..329
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 330..366
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 367..387
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 388..405
FT /note="Periplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 427..460
FT /note="Cytoplasmic"
FT /evidence="ECO:0000269|PubMed:15919996, ECO:0000305"
FT CONFLICT 370
FT /note="K -> N (in Ref. 1; AAB08691)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 460 AA; 50632 MW; AB600588E663C6B7 CRC64;
MTQLTMKDKI GYGLGDTACG FVWQATMFLL AYFYTDVFGL SAGIMGTLFL VSRVLDAVTD
PLMGLLVDRT RTRHGQFRPF LLWGAIPFGI VCVLTFYTPD FSAQGKIIYA CVTYILLTLV
YTFVNVPYCA MPGVITADPK ERHALQSWRF FLAAAGSLAI SGIALPLVSI IGKGDEQVGY
FGAMCVLGLS GVVLLYVCFF TTKERYTFEV QPGSSVAKDL KLLLGNSQWR IMCAFKMMAT
CSNVVRGGAT LYFVKYVMDH PELATQFLLY GSLATMFGSL CSSRLLGRFD RVTAFKWIIV
AYSLISLLIF VTPAEHIALI FALNILFLFV FNTTTPLQWL MASDVVDYEE SRSGRRLDGL
VFSTYLFSLK IGLAIGGAVV GWILAYVNYS ASSSVQPVEV LTTIKILFCV VPVVLYAGMF
IMLSLYKLTD ARVEAISRQL IKHRAAQGEA VPDAATAASH
