YAGU_ECOLI
ID YAGU_ECOLI Reviewed; 204 AA.
AC P0AAA1; P77262; Q2MCD5;
DT 13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT 13-SEP-2005, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Inner membrane protein YagU;
GN Name=yagU; OrderedLocusNames=b0287, JW0281;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RA Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT "Sequence of minutes 4-25 of Escherichia coli.";
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP SUBUNIT, AND SUBCELLULAR LOCATION.
RC STRAIN=BL21-DE3;
RX PubMed=16079137; DOI=10.1074/jbc.m506479200;
RA Stenberg F., Chovanec P., Maslen S.L., Robinson C.V., Ilag L.,
RA von Heijne G., Daley D.O.;
RT "Protein complexes of the Escherichia coli cell envelope.";
RL J. Biol. Chem. 280:34409-34419(2005).
RN [5]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBUNIT: Homodimer. {ECO:0000269|PubMed:16079137}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000269|PubMed:16079137}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:16079137}.
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DR EMBL; U73857; AAB18016.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73390.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76071.1; -; Genomic_DNA.
DR PIR; G64754; G64754.
DR RefSeq; NP_414821.1; NC_000913.3.
DR RefSeq; WP_001019920.1; NZ_STEB01000020.1.
DR AlphaFoldDB; P0AAA1; -.
DR SMR; P0AAA1; -.
DR BioGRID; 4259787; 6.
DR STRING; 511145.b0287; -.
DR jPOST; P0AAA1; -.
DR PaxDb; P0AAA1; -.
DR PRIDE; P0AAA1; -.
DR EnsemblBacteria; AAC73390; AAC73390; b0287.
DR EnsemblBacteria; BAE76071; BAE76071; BAE76071.
DR GeneID; 66671418; -.
DR GeneID; 945677; -.
DR KEGG; ecj:JW0281; -.
DR KEGG; eco:b0287; -.
DR PATRIC; fig|1411691.4.peg.1990; -.
DR EchoBASE; EB3330; -.
DR eggNOG; COG3477; Bacteria.
DR HOGENOM; CLU_095313_0_0_6; -.
DR OMA; DQKVFWF; -.
DR PhylomeDB; P0AAA1; -.
DR BioCyc; EcoCyc:G6158-MON; -.
DR PRO; PR:P0AAA1; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0010447; P:response to acidic pH; IMP:EcoCyc.
DR InterPro; IPR009898; DUF1440.
DR Pfam; PF07274; DUF1440; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..204
FT /note="Inner membrane protein YagU"
FT /id="PRO_0000168563"
FT TOPO_DOM 1..14
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 36..100
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 122..132
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 154..204
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 204 AA; 22967 MW; 57EA63ED66B2E6C8 CRC64;
MNIFEQTPPN RRRYGLAAFI GLIAGVVSAF VKWGAEVPLP PRSPVDMFNA ACGPESLIRA
AGQIDCSRNF LNPPYIFLRD WLGLTDPNAA VYTFAGHVFN WVGVTHIIFS IVFAVGYCVV
AEVFPKIKLW QGLLAGALAQ LFVHMISFPL MGLTPPLFDL PWYENVSEIF GHLVWFWSIE
IIRRDLRNRI THEPDPEIPL GSNR
