ID   CATC_CUPPJ              Reviewed;          92 AA.
AC   P80573; Q470X8;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 2.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Muconolactone Delta-isomerase;
DE            Short=MIase;
DE            EC=5.3.3.4 {ECO:0000250|UniProtKB:P00948};
GN   Name=catC; OrderedLocusNames=Reut_A1690;
OS   Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Cupriavidus necator
OS   (strain JMP 134)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=264198;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JMP134 / LMG 1197;
RX   PubMed=20339589; DOI=10.1371/journal.pone.0009729;
RA   Lykidis A., Perez-Pantoja D., Ledger T., Mavromatis K., Anderson I.J.,
RA   Ivanova N.N., Hooper S.D., Lapidus A., Lucas S., Gonzalez B.,
RA   Kyrpides N.C.;
RT   "The complete multipartite genome sequence of Cupriavidus necator JMP134, a
RT   versatile pollutant degrader.";
RL   PLoS ONE 5:E9729-E9729(2010).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-48, SUBUNIT, AND CHARACTERIZATION.
RX   PubMed=8647072; DOI=10.1111/j.1432-1033.1996.00350.x;
RA   Prucha M., Peterseim A., Timmis K.N., Pieper D.H.;
RT   "Muconolactone isomerase of the 3-oxoadipate pathway catalyzes
RT   dechlorination of 5-chloro-substituted muconolactones.";
RL   Eur. J. Biochem. 237:350-356(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-muconolactone = (4,5-dihydro-5-oxofuran-2-yl)-acetate;
CC         Xref=Rhea:RHEA:12348, ChEBI:CHEBI:58425, ChEBI:CHEBI:58736;
CC         EC=5.3.3.4; Evidence={ECO:0000250|UniProtKB:P00948};
CC   -!- PATHWAY: Aromatic compound metabolism; beta-ketoadipate pathway; 5-oxo-
CC       4,5-dihydro-2-furylacetate from catechol: step 3/3.
CC   -!- SUBUNIT: Homodecamer. {ECO:0000269|PubMed:8647072}.
CC   -!- SIMILARITY: Belongs to the muconolactone Delta-isomerase family.
CC       {ECO:0000305}.
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DR   EMBL; CP000090; AAZ61055.1; -; Genomic_DNA.
DR   RefSeq; WP_011297853.1; NC_007347.1.
DR   AlphaFoldDB; P80573; -.
DR   SMR; P80573; -.
DR   STRING; 264198.Reut_A1690; -.
DR   EnsemblBacteria; AAZ61055; AAZ61055; Reut_A1690.
DR   KEGG; reu:Reut_A1690; -.
DR   eggNOG; COG4829; Bacteria.
DR   HOGENOM; CLU_080702_2_0_4; -.
DR   OMA; WRVPGRN; -.
DR   OrthoDB; 1857318at2; -.
DR   BioCyc; MetaCyc:MON-14657; -.
DR   UniPathway; UPA00157; UER00260.
DR   GO; GO:0016159; F:muconolactone delta-isomerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042952; P:beta-ketoadipate pathway; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR026029; MLI_dom.
DR   InterPro; IPR003464; Muconolactone_d_Isoase.
DR   Pfam; PF02426; MIase; 1.
DR   PIRSF; PIRSF001486; CatC; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   TIGRFAMs; TIGR03221; muco_delta; 1.
PE   1: Evidence at protein level;
KW   Aromatic hydrocarbons catabolism; Direct protein sequencing; Isomerase.
FT   CHAIN           1..92
FT                   /note="Muconolactone Delta-isomerase"
FT                   /id="PRO_0000089335"
FT   CONFLICT        10
FT                   /note="N -> D (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        14
FT                   /note="D -> N (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        40
FT                   /note="W -> T (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   92 AA;  10604 MW;  A0DD51643875825E CRC64;
     MLYLVRMDVN LPHDMPAAQA DDIKAREKAY AQQLQHEGKW QQLYRVVGEY ANYSIFDVGS
     HDELHTLLSG LPLFPYMKIH VTPLAKHPSS IR