ID   YAHN_ECOLI              Reviewed;         223 AA.
AC   P75693; P71307; Q2MC95;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 133.
DE   RecName: Full=Uncharacterized membrane protein YahN;
GN   Name=yahN; OrderedLocusNames=b0328, JW0320;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RA   Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA   Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA   Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT   "Sequence of minutes 4-25 of Escherichia coli.";
RL   Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the Rht family. {ECO:0000305}.
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DR   EMBL; U73857; AAB18053.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC73431.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76111.1; -; Genomic_DNA.
DR   PIR; H64759; H64759.
DR   RefSeq; NP_414862.1; NC_000913.3.
DR   RefSeq; WP_000983410.1; NZ_SSZK01000063.1.
DR   AlphaFoldDB; P75693; -.
DR   BioGRID; 4259805; 9.
DR   BioGRID; 849365; 1.
DR   IntAct; P75693; 3.
DR   STRING; 511145.b0328; -.
DR   TCDB; 2.A.76.1.3; the resistance to homoserine/threonine (rhtb) family.
DR   PaxDb; P75693; -.
DR   PRIDE; P75693; -.
DR   EnsemblBacteria; AAC73431; AAC73431; b0328.
DR   EnsemblBacteria; BAE76111; BAE76111; BAE76111.
DR   GeneID; 944968; -.
DR   KEGG; ecj:JW0320; -.
DR   KEGG; eco:b0328; -.
DR   PATRIC; fig|511145.12.peg.334; -.
DR   EchoBASE; EB3367; -.
DR   eggNOG; COG1280; Bacteria.
DR   HOGENOM; CLU_079569_0_2_6; -.
DR   InParanoid; P75693; -.
DR   OMA; SVIWRVF; -.
DR   PhylomeDB; P75693; -.
DR   BioCyc; EcoCyc:G6193-MON; -.
DR   PRO; PR:P75693; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0006865; P:amino acid transport; IBA:GO_Central.
DR   InterPro; IPR004778; Homoserine/Threonine_efflux.
DR   InterPro; IPR001123; LeuE-type.
DR   PANTHER; PTHR30086; PTHR30086; 1.
DR   Pfam; PF01810; LysE; 1.
DR   PIRSF; PIRSF006324; LeuE; 1.
DR   TIGRFAMs; TIGR00949; 2A76; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..223
FT                   /note="Uncharacterized membrane protein YahN"
FT                   /id="PRO_0000094741"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        213..223
FT                   /note="LRLIYEGVTQR -> YA (in Ref. 1; AAB18053)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   223 AA;  24811 MW;  E17F5ABC31EE3F26 CRC64;
     MMQLVHLFMD EITMDPLHAV YLTVGLFVIT FFNPGANLFV VVQTSLASGR RAGVLTGLGV
     ALGDAFYSGL GLFGLATLIT QCEEIFSLIR IVGGAYLLWF AWCSMRRQST PQMSTLQQPI
     SAPWYVFFRR GLITDLSNPQ TVLFFISIFS VTLNAETPTW ARLMAWAGIV LASIIWRVFL
     SQAFSLPAVR RAYGRMQRVA SRVIGAIIGV FALRLIYEGV TQR