ID   CATC_PSEAE              Reviewed;          96 AA.
AC   Q9I0X4;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Muconolactone Delta-isomerase;
DE            Short=MIase;
DE            EC=5.3.3.4 {ECO:0000250|UniProtKB:P00948};
GN   Name=catC; OrderedLocusNames=PA2508;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-muconolactone = (4,5-dihydro-5-oxofuran-2-yl)-acetate;
CC         Xref=Rhea:RHEA:12348, ChEBI:CHEBI:58425, ChEBI:CHEBI:58736;
CC         EC=5.3.3.4; Evidence={ECO:0000250|UniProtKB:P00948};
CC   -!- PATHWAY: Aromatic compound metabolism; beta-ketoadipate pathway; 5-oxo-
CC       4,5-dihydro-2-furylacetate from catechol: step 3/3.
CC   -!- SUBUNIT: Homodecamer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the muconolactone Delta-isomerase family.
CC       {ECO:0000305}.
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DR   EMBL; AE004091; AAG05896.1; -; Genomic_DNA.
DR   PIR; C83331; C83331.
DR   RefSeq; NP_251198.1; NC_002516.2.
DR   RefSeq; WP_003089864.1; NZ_QZGE01000008.1.
DR   AlphaFoldDB; Q9I0X4; -.
DR   SMR; Q9I0X4; -.
DR   STRING; 287.DR97_5664; -.
DR   PaxDb; Q9I0X4; -.
DR   EnsemblBacteria; AAG05896; AAG05896; PA2508.
DR   GeneID; 882967; -.
DR   KEGG; pae:PA2508; -.
DR   PATRIC; fig|208964.12.peg.2620; -.
DR   PseudoCAP; PA2508; -.
DR   HOGENOM; CLU_080702_2_0_6; -.
DR   OMA; MCRHPSS; -.
DR   PhylomeDB; Q9I0X4; -.
DR   BioCyc; PAER208964:G1FZ6-2543-MON; -.
DR   UniPathway; UPA00157; UER00260.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0016159; F:muconolactone delta-isomerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0042952; P:beta-ketoadipate pathway; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR026029; MLI_dom.
DR   InterPro; IPR003464; Muconolactone_d_Isoase.
DR   Pfam; PF02426; MIase; 1.
DR   PIRSF; PIRSF001486; CatC; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   TIGRFAMs; TIGR03221; muco_delta; 1.
PE   3: Inferred from homology;
KW   Aromatic hydrocarbons catabolism; Isomerase; Reference proteome.
FT   CHAIN           1..96
FT                   /note="Muconolactone Delta-isomerase"
FT                   /id="PRO_0000287786"
SQ   SEQUENCE   96 AA;  11314 MW;  F63077EF88E417E2 CRC64;
     MLFHVKMTVK LPVDMDPQQA ERLKAEEKEM AQRLQREGSW RHLWRIAGHY ANYSLFDLPS
     VEALHDTLTR LPLFPYMDIE IDGLCRHPSS IHADDR