CATC_PSEPU
ID CATC_PSEPU Reviewed; 96 AA.
AC P00948; Q51959;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 15-JUL-1999, sequence version 3.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Muconolactone Delta-isomerase;
DE Short=MIase;
DE EC=5.3.3.4 {ECO:0000269|PubMed:5330966};
GN Name=catC;
OS Pseudomonas putida (Arthrobacter siderocapsulatus).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=303;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2449420; DOI=10.1128/jb.170.3.1297-1304.1988;
RA Aldrich T.L., Chakrabarty A.M.;
RT "Transcriptional regulation, nucleotide sequence, and localization of the
RT promoter of the catBC operon in Pseudomonas putida.";
RL J. Bacteriol. 170:1297-1304(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=PRS2000;
RX PubMed=7814330; DOI=10.1128/jb.177.2.401-412.1995;
RA Houghton J.E., Brown T.M., Appel A.J., Hughes E.J., Ornston L.N.;
RT "Discontinuities in the evolution of Pseudomonas putida cat genes.";
RL J. Bacteriol. 177:401-412(1995).
RN [3]
RP PROTEIN SEQUENCE OF 1-52.
RX PubMed=7391022; DOI=10.1016/s0021-9258(18)43742-8;
RA McCorkle G.M., Yeh W.-K., Fletcher P., Ornston L.N.;
RT "Repetitions in the NH2-terminal amino acid sequence of beta-ketoadipate
RT enol-lactone hydrolase from Pseudomonas putida.";
RL J. Biol. Chem. 255:6335-6341(1980).
RN [4]
RP PARTIAL PROTEIN SEQUENCE.
RC STRAIN=PRS2113;
RX PubMed=901811; DOI=10.1016/0005-2795(77)90132-5;
RA Meagher R.B.;
RT "Purification and partial amino acid sequence of the cyanogen bromide
RT fragments of muconolactone isomerase from Pseudomonas putida.";
RL Biochim. Biophys. Acta 494:33-47(1977).
RN [5]
RP CATALYTIC ACTIVITY.
RX PubMed=5330966; DOI=10.1016/s0021-9258(18)99841-8;
RA Ornston L.N.;
RT "The conversion of catechol and protocatechuate to beta-ketoadipate by
RT Pseudomonas putida. 3. Enzymes of the catechol pathway.";
RL J. Biol. Chem. 241:3795-3799(1966).
RN [6]
RP X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS).
RX PubMed=2926818; DOI=10.1016/0022-2836(89)90226-x;
RA Katti S.K., Katz B.A., Wyckoff H.W.;
RT "Crystal structure of muconolactone isomerase at 3.3-A resolution.";
RL J. Mol. Biol. 205:557-571(1989).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-muconolactone = (4,5-dihydro-5-oxofuran-2-yl)-acetate;
CC Xref=Rhea:RHEA:12348, ChEBI:CHEBI:58425, ChEBI:CHEBI:58736;
CC EC=5.3.3.4; Evidence={ECO:0000269|PubMed:5330966};
CC -!- PATHWAY: Aromatic compound metabolism; beta-ketoadipate pathway; 5-oxo-
CC 4,5-dihydro-2-furylacetate from catechol: step 3/3.
CC -!- SUBUNIT: Homodecamer.
CC -!- SIMILARITY: Belongs to the muconolactone Delta-isomerase family.
CC {ECO:0000305}.
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DR EMBL; M19460; AAA25767.1; -; Genomic_DNA.
DR EMBL; U12557; AAA66203.1; -; Genomic_DNA.
DR PIR; B28630; ISPSMP.
DR PDB; 1MLI; X-ray; 3.30 A; A/B/C/D/E/F/G/H/I/J=1-96.
DR PDBsum; 1MLI; -.
DR AlphaFoldDB; P00948; -.
DR SMR; P00948; -.
DR STRING; 1240350.AMZE01000026_gene4645; -.
DR PRIDE; P00948; -.
DR KEGG; ag:AAA66203; -.
DR eggNOG; COG4829; Bacteria.
DR BioCyc; MetaCyc:MON-3424; -.
DR UniPathway; UPA00157; UER00260.
DR EvolutionaryTrace; P00948; -.
DR GO; GO:0016159; F:muconolactone delta-isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0042952; P:beta-ketoadipate pathway; IEA:UniProtKB-UniPathway.
DR InterPro; IPR011008; Dimeric_a/b-barrel.
DR InterPro; IPR026029; MLI_dom.
DR InterPro; IPR003464; Muconolactone_d_Isoase.
DR Pfam; PF02426; MIase; 1.
DR PIRSF; PIRSF001486; CatC; 1.
DR SUPFAM; SSF54909; SSF54909; 1.
DR TIGRFAMs; TIGR03221; muco_delta; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Aromatic hydrocarbons catabolism; Direct protein sequencing;
KW Isomerase.
FT CHAIN 1..96
FT /note="Muconolactone Delta-isomerase"
FT /id="PRO_0000089334"
FT CONFLICT 21..22
FT /note="TQ -> AR (in Ref. 1; AAA25767)"
FT /evidence="ECO:0000305"
FT CONFLICT 47
FT /note="A -> AV (in Ref. 1; AAA25767)"
FT /evidence="ECO:0000305"
FT CONFLICT 59
FT /note="S -> P (in Ref. 2; AAA66203)"
FT /evidence="ECO:0000305"
FT CONFLICT 64..65
FT /note="CN -> LH (in Ref. 2; AAA66203)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 96 AA; 11116 MW; 0BD82946E0636D14 CRC64;
MLFHVKMTVK LPVDMDPAKA TQLKADEKEL AQRLQREGTW RHLWRIAGHY ANYSVFDVSS
VEACNDTLMQ LPLFPYMDIE VDGLCRHPSS IHSDDR
