YAJC_BORBU
ID YAJC_BORBU Reviewed; 105 AA.
AC O51595;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 25-MAY-2022, entry version 114.
DE RecName: Full=Sec translocon accessory complex subunit YajC;
GN Name=yajC; OrderedLocusNames=BB_0651;
OS Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
OS (Borrelia burgdorferi).
OC Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX NCBI_TaxID=224326;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35210 / DSM 4680 / CIP 102532 / B31;
RX PubMed=9403685; DOI=10.1038/37551;
RA Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L.,
RA Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L.,
RA Peterson J.D., Kerlavage A.R., Quackenbush J., Salzberg S.L., Hanson M.,
RA van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F.,
RA Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C.,
RA Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B.,
RA Smith H.O., Venter J.C.;
RT "Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.";
RL Nature 390:580-586(1997).
CC -!- FUNCTION: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein
CC secretase/insertase is a supercomplex required for protein secretion,
CC insertion of proteins into membranes, and assembly of membrane protein
CC complexes. While the SecYEG complex is essential for assembly of a
CC number of proteins and complexes, the SecDF-YajC-YidC subcomplex
CC facilitates these functions. {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SUBUNIT: Part of the SecDF-YidC-YajC translocase complex. The SecDF-
CC YidC-YajC translocase forms a supercomplex with SecYEG, called the
CC holo-translocon (HTL). {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000250|UniProtKB:P0ADZ7}; Single-pass membrane protein
CC {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SIMILARITY: Belongs to the YajC family. {ECO:0000305}.
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DR EMBL; AE000783; AAC66994.1; -; Genomic_DNA.
DR PIR; B70181; B70181.
DR RefSeq; NP_212785.1; NC_001318.1.
DR RefSeq; WP_002657363.1; NC_001318.1.
DR AlphaFoldDB; O51595; -.
DR SMR; O51595; -.
DR STRING; 224326.BB_0651; -.
DR PRIDE; O51595; -.
DR EnsemblBacteria; AAC66994; AAC66994; BB_0651.
DR GeneID; 56567461; -.
DR KEGG; bbu:BB_0651; -.
DR PATRIC; fig|224326.49.peg.1042; -.
DR HOGENOM; CLU_116157_5_2_12; -.
DR OMA; GMEMIIM; -.
DR Proteomes; UP000001807; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR003849; Preprotein_translocase_YajC.
DR PANTHER; PTHR33909; PTHR33909; 1.
DR Pfam; PF02699; YajC; 1.
DR PRINTS; PR01853; YAJCTRNLCASE.
DR SMART; SM01323; YajC; 1.
DR TIGRFAMs; TIGR00739; yajC; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW Reference proteome; Translocation; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..105
FT /note="Sec translocon accessory complex subunit YajC"
FT /id="PRO_0000097021"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 105 AA; 11840 MW; F7DD1A898E2396CE CRC64;
MYSMGGFVFL LQEFSGNSSF LRSLLVFVPV IAIFWFLVIS PQRKEEKNKK EMIKNLKKGD
KVLTIGGIFG VVKKLGDTDV ILELSPNNEA VFIKNSIDKV LSEKK