YAJC_BRUA2
ID YAJC_BRUA2 Reviewed; 113 AA.
AC Q2YNM1; P0A4Q3; Q57DL7; Q9ZG87;
DT 07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=Sec translocon accessory complex subunit YajC;
DE AltName: Full=Immunogenic membrane protein YajC;
GN Name=yajC; OrderedLocusNames=BAB1_0909;
OS Brucella abortus (strain 2308).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=359391;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9826342; DOI=10.1128/iai.66.12.5684-5691.1998;
RA Vemulapalli R., Duncan A.J., Boyle S.M., Sriranganathan N., Toth T.E.,
RA Schurig G.G.;
RT "Cloning and sequencing of yajC and secD homologs of Brucella abortus and
RT demonstration of immune responses to YajC in mice vaccinated with B.
RT abortus RB51.";
RL Infect. Immun. 66:5684-5691(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2308;
RX PubMed=16299333; DOI=10.1128/iai.73.12.8353-8361.2005;
RA Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A.,
RA Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.;
RT "Whole-genome analyses of speciation events in pathogenic Brucellae.";
RL Infect. Immun. 73:8353-8361(2005).
CC -!- FUNCTION: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein
CC secretase/insertase is a supercomplex required for protein secretion,
CC insertion of proteins into membranes, and assembly of membrane protein
CC complexes. While the SecYEG complex is essential for assembly of a
CC number of proteins and complexes, the SecDF-YajC-YidC subcomplex
CC facilitates these functions. {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SUBUNIT: Part of the SecDF-YidC-YajC translocase complex. The SecDF-
CC YidC-YajC translocase forms a supercomplex with SecYEG, called the
CC holo-translocon (HTL). {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000250|UniProtKB:P0ADZ7}; Single-pass membrane protein
CC {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SIMILARITY: Belongs to the YajC family. {ECO:0000305}.
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DR EMBL; AF085217; AAC83690.1; -; Genomic_DNA.
DR EMBL; AM040264; CAJ10865.1; -; Genomic_DNA.
DR RefSeq; WP_002964021.1; NZ_KN046823.1.
DR AlphaFoldDB; Q2YNM1; -.
DR SMR; Q2YNM1; -.
DR STRING; 359391.BAB1_0909; -.
DR EnsemblBacteria; CAJ10865; CAJ10865; BAB1_0909.
DR GeneID; 45051954; -.
DR GeneID; 55590596; -.
DR KEGG; bmf:BAB1_0909; -.
DR PATRIC; fig|359391.11.peg.3219; -.
DR HOGENOM; CLU_116157_2_0_5; -.
DR OMA; GMEMIIM; -.
DR PhylomeDB; Q2YNM1; -.
DR Proteomes; UP000002719; Chromosome I.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR003849; Preprotein_translocase_YajC.
DR PANTHER; PTHR33909; PTHR33909; 1.
DR Pfam; PF02699; YajC; 1.
DR PRINTS; PR01853; YAJCTRNLCASE.
DR SMART; SM01323; YajC; 1.
DR TIGRFAMs; TIGR00739; yajC; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW Reference proteome; Translocation; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..113
FT /note="Sec translocon accessory complex subunit YajC"
FT /id="PRO_0000097023"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 113 AA; 12560 MW; 9B1C0FB65DA9E2D5 CRC64;
MFVTPAFAQA SGSVVGPDML MSILPFILIF VIMYFLIIRP QRTQMKKRQE MLNSVRRGDT
VVTGGGIVGK VLKVVDDNEL ELEIADGVRI RVVRATLMDV RVKGEPVADN KNK