YAJC_BRUME
ID YAJC_BRUME Reviewed; 113 AA.
AC P0A4Q1; Q9ZG87;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Sec translocon accessory complex subunit YajC;
DE AltName: Full=Immunogenic membrane protein YajC;
GN Name=yajC; OrderedLocusNames=BMEI1077;
OS Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=224914;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / NCTC 10094;
RX PubMed=11756688; DOI=10.1073/pnas.221575398;
RA DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA Haselkorn R., Kyrpides N.C., Overbeek R.;
RT "The genome sequence of the facultative intracellular pathogen Brucella
RT melitensis.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC -!- FUNCTION: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein
CC secretase/insertase is a supercomplex required for protein secretion,
CC insertion of proteins into membranes, and assembly of membrane protein
CC complexes. While the SecYEG complex is essential for assembly of a
CC number of proteins and complexes, the SecDF-YajC-YidC subcomplex
CC facilitates these functions. {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SUBUNIT: Part of the SecDF-YidC-YajC translocase complex. The SecDF-
CC YidC-YajC translocase forms a supercomplex with SecYEG, called the
CC holo-translocon (HTL). {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000250|UniProtKB:P0ADZ7}; Single-pass membrane protein
CC {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SIMILARITY: Belongs to the YajC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAL52258.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AE008917; AAL52258.1; ALT_INIT; Genomic_DNA.
DR PIR; AG3386; AG3386.
DR RefSeq; WP_002964021.1; NZ_GG703778.1.
DR AlphaFoldDB; P0A4Q1; -.
DR SMR; P0A4Q1; -.
DR STRING; 224914.BMEI1077; -.
DR EnsemblBacteria; AAL52258; AAL52258; BMEI1077.
DR GeneID; 45051954; -.
DR GeneID; 55590596; -.
DR KEGG; bme:BMEI1077; -.
DR PATRIC; fig|224914.52.peg.348; -.
DR eggNOG; COG1862; Bacteria.
DR OMA; GMEMIIM; -.
DR PhylomeDB; P0A4Q1; -.
DR Proteomes; UP000000419; Chromosome I.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR003849; Preprotein_translocase_YajC.
DR PANTHER; PTHR33909; PTHR33909; 1.
DR Pfam; PF02699; YajC; 1.
DR PRINTS; PR01853; YAJCTRNLCASE.
DR SMART; SM01323; YajC; 1.
DR TIGRFAMs; TIGR00739; yajC; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW Translocation; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..113
FT /note="Sec translocon accessory complex subunit YajC"
FT /id="PRO_0000097024"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 113 AA; 12560 MW; 9B1C0FB65DA9E2D5 CRC64;
MFVTPAFAQA SGSVVGPDML MSILPFILIF VIMYFLIIRP QRTQMKKRQE MLNSVRRGDT
VVTGGGIVGK VLKVVDDNEL ELEIADGVRI RVVRATLMDV RVKGEPVADN KNK
