YAJC_CHLTR
ID YAJC_CHLTR Reviewed; 114 AA.
AC O84746;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 101.
DE RecName: Full=Sec translocon accessory complex subunit YajC;
GN Name=yajC; OrderedLocusNames=CT_741;
OS Chlamydia trachomatis (strain D/UW-3/Cx).
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=272561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D/UW-3/Cx;
RX PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
RT "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia
RT trachomatis.";
RL Science 282:754-759(1998).
CC -!- FUNCTION: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein
CC secretase/insertase is a supercomplex required for protein secretion,
CC insertion of proteins into membranes, and assembly of membrane protein
CC complexes. While the SecYEG complex is essential for assembly of a
CC number of proteins and complexes, the SecDF-YajC-YidC subcomplex
CC facilitates these functions. {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SUBUNIT: Part of the SecDF-YidC-YajC translocase complex. The SecDF-
CC YidC-YajC translocase forms a supercomplex with SecYEG, called the
CC holo-translocon (HTL). {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000250|UniProtKB:P0ADZ7}; Single-pass membrane protein
CC {ECO:0000250|UniProtKB:P0ADZ7}.
CC -!- SIMILARITY: Belongs to the YajC family. {ECO:0000305}.
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DR EMBL; AE001273; AAC68336.1; -; Genomic_DNA.
DR PIR; G71476; G71476.
DR RefSeq; NP_220260.1; NC_000117.1.
DR RefSeq; WP_009872119.1; NC_000117.1.
DR AlphaFoldDB; O84746; -.
DR SMR; O84746; -.
DR STRING; 813.O172_04115; -.
DR EnsemblBacteria; AAC68336; AAC68336; CT_741.
DR GeneID; 884535; -.
DR KEGG; ctr:CT_741; -.
DR PATRIC; fig|272561.5.peg.815; -.
DR HOGENOM; CLU_116157_2_2_0; -.
DR InParanoid; O84746; -.
DR OMA; RLFMCFL; -.
DR Proteomes; UP000000431; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR003849; Preprotein_translocase_YajC.
DR PANTHER; PTHR33909; PTHR33909; 1.
DR Pfam; PF02699; YajC; 1.
DR PRINTS; PR01853; YAJCTRNLCASE.
DR SMART; SM01323; YajC; 1.
DR TIGRFAMs; TIGR00739; yajC; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW Reference proteome; Translocation; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..114
FT /note="Sec translocon accessory complex subunit YajC"
FT /id="PRO_0000097031"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 114 AA; 12784 MW; 008542BBB0D4F30F CRC64;
MYSRLFFSIL FFLGCCPALF ADTDSPQRAT FGQPAVMLGI AIVFFYFILW RPEQKRRQAM
EKRKSELAVG DKVTAMGIVG TIAEIREHTV ILNIASGKIE ILKAAISEIL KAEK