ID   YAJC_ECOL6              Reviewed;         110 AA.
AC   P0ADZ8; P19677;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Sec translocon accessory complex subunit YajC;
GN   Name=yajC; OrderedLocusNames=c0517;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein
CC       secretase/insertase is a supercomplex required for protein secretion,
CC       insertion of proteins into membranes, and assembly of membrane protein
CC       complexes. While the SecYEG complex is essential for assembly of a
CC       number of proteins and complexes, the SecDF-YajC-YidC subcomplex
CC       facilitates these functions. {ECO:0000250|UniProtKB:P0ADZ7}.
CC   -!- SUBUNIT: Part of the SecDF-YidC-YajC translocase complex. The SecDF-
CC       YidC-YajC translocase forms a supercomplex with SecYEG, called the
CC       holo-translocon (HTL). {ECO:0000250|UniProtKB:P0ADZ7}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000250|UniProtKB:P0ADZ7}; Single-pass membrane protein
CC       {ECO:0000250|UniProtKB:P0ADZ7}.
CC   -!- SIMILARITY: Belongs to the YajC family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN78995.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AE014075; AAN78995.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000007629.1; NC_004431.1.
DR   AlphaFoldDB; P0ADZ8; -.
DR   SMR; P0ADZ8; -.
DR   STRING; 199310.c0517; -.
DR   EnsemblBacteria; AAN78995; AAN78995; c0517.
DR   GeneID; 67416520; -.
DR   KEGG; ecc:c0517; -.
DR   eggNOG; COG1862; Bacteria.
DR   HOGENOM; CLU_116157_2_1_6; -.
DR   OMA; GMEMIIM; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003849; Preprotein_translocase_YajC.
DR   PANTHER; PTHR33909; PTHR33909; 1.
DR   Pfam; PF02699; YajC; 1.
DR   PRINTS; PR01853; YAJCTRNLCASE.
DR   SMART; SM01323; YajC; 1.
DR   TIGRFAMs; TIGR00739; yajC; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Translocation; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..110
FT                   /note="Sec translocon accessory complex subunit YajC"
FT                   /id="PRO_0000097015"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   110 AA;  11887 MW;  8E90AF51F0205306 CRC64;
     MSFFISDAVA ATGAPAQGSP MSLILMLVVF GLIFYFMILR PQQKRTKEHK KLMDSIAKGD
     EVLTNGGLVG RVTKVAENGY IAIALNDTTE VVIKRDFVAA VLPKGTMKAL