位置:首页 > 蛋白库 > YAJC_MYCBO
YAJC_MYCBO
ID   YAJC_MYCBO              Reviewed;         115 AA.
AC   P65026; A0A1R3Y1W0; Q50633; X2BLD3;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Sec translocon accessory complex subunit YajC;
GN   Name=yajC; OrderedLocusNames=BQ2027_MB2619C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- FUNCTION: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein
CC       secretase/insertase is a supercomplex required for protein secretion,
CC       insertion of proteins into membranes, and assembly of membrane protein
CC       complexes. While the SecYEG complex is essential for assembly of a
CC       number of proteins and complexes, the SecDF-YajC-YidC subcomplex
CC       facilitates these functions. {ECO:0000250|UniProtKB:P0ADZ7}.
CC   -!- SUBUNIT: Part of the SecDF-YidC-YajC translocase complex. The SecDF-
CC       YidC-YajC translocase forms a supercomplex with SecYEG, called the
CC       holo-translocon (HTL). {ECO:0000250|UniProtKB:P0ADZ7}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255}; Single-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the YajC family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LT708304; SIU01237.1; -; Genomic_DNA.
DR   RefSeq; NP_856265.1; NC_002945.3.
DR   RefSeq; WP_003413391.1; NC_002945.4.
DR   AlphaFoldDB; P65026; -.
DR   SMR; P65026; -.
DR   EnsemblBacteria; SIU01237; SIU01237; BQ2027_MB2619C.
DR   GeneID; 45426590; -.
DR   PATRIC; fig|233413.5.peg.2880; -.
DR   OMA; GVMYFMM; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003849; Preprotein_translocase_YajC.
DR   PANTHER; PTHR33909; PTHR33909; 1.
DR   Pfam; PF02699; YajC; 1.
DR   SMART; SM01323; YajC; 1.
DR   TIGRFAMs; TIGR00739; yajC; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Protein transport; Translocation; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..115
FT                   /note="Sec translocon accessory complex subunit YajC"
FT                   /id="PRO_0000014140"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          96..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   115 AA;  12967 MW;  5DACBA453C1F7C12 CRC64;
     MESFVLFLPF LLIMGGFMYF ASRRQRRAMQ ATIDLHDSLQ PGERVHTTSG LEATIVAIAD
     DTIDLEIAPG VVTTWMKLAI RDRILPDDDI DEELNEDLDK DVDDVAGERR VTNDS
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024